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This book reviews the potential effect of diet modification, lipids, and carbohydrate consumptions, vitamin supplementation, antioxidants, and nutraceuticals in the prevention and management of Alzheimer's disease. The initial chapter of the book presents the pathophysiological mechanisms, risk factors, genetic predisposition, disease diagnosis, pathology, and current treatment strategies against Alzheimer's disease. It also highlights recent developments in exploring novel compounds for the prevention and treatment of Alzheimer's disease. Subsequently, it highlights the therapeutic effect and regulation of molecular targets by natural compounds. The book discusses the potential of natural compounds in inhibiting the formation and deposition of Aß peptides. It examines the natural compounds in modulating intracellular signaling molecules and enzymes involved in the pathogenesis of Alzheimer's disease. In summary, this book helps understand the role of natural compounds as a therapeutic approach in amelioration and preventing detrimental effects of Alzheimer's disease.
Dr. A. Justin Thenmozhi is working as an Assistant Professor in the Department of Biochemistry, School of Biological Sciences, Madurai Kamaraj University, India. Earlier she served as an Assistant Professor in the Department of Biochemistry and Biotechnology, Annamalai University and Idhaya College for Women, Kumbakonam. She has an expertise in the field of Nutritional Neuroscience and Neuropharmacology and has published more than 60 research articles in peer reviewed international journals, has edited 2 books, and 21 book chapters in Neuroscience. Her books entitled "Food and Huntington's disease" and "Food and Parkinson's disease" were awarded as best books in the world by GOURMAND Cook Book Awards. She is the Fellow of "Academy of Sciences", Chennai. She is holding membership in various international and national neuroscience societies. She has received the best researcher awards from the Annamalai University (2017- 2018 & 2018-2019) and has served as an editor/reviewer for various peer reviewed international journals including, Journal of Alzheimer's disease, Neurochemical Research, Neurotoxicity Research, Chemico-Biological Interactions etc.
Dr. T. Manivasagam is an Assistant Professor in the Department of Biochemistry and Biotechnology, Annamalai University. His research interests are in neuroscience with specialization in cellular and animal models of Parkinson's disease, Alzheimer's disease and Autism, and drug discovery from plant products. He has published more than 100 research articles in the peer-reviewed international journals, edited 3 books, and authored or co-authored 50 book chapters. He has more than 15 years of teaching experience in Biochemistry and had received young scientist award from the Annamalai University and the Academy of Sciences, Chennai.
Module 1_Introduction, pathology, genetics and current medications of AD.- Module 2_Effect of diet patterns at the cellular and molecular levels in AD.- Module 3_Specific phytochemicals and food substances as a therapy for AD.- Module 4_Role of medicinal plant in the management of AD. -Module 5_Probiotic and dietary interventions in AD.- Module 6_Advantages and disadvantages of nutraceuticals during AD.
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