The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders.
- Discusses the importance of the hypothalamus in human growth and development
- Reviews hypothalamic related tumors, as well as pituitary, autoimmune, vasopressin and hormone regulation disorders
- Includes metabolic and eating disorders
- Identifies mechanisms of disease action and etiology
- Provides best practice information for assessment and treatment
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-12-820684-3 (9780128206843)
Schweitzer Klassifikation
1. Introduction: The human hypothalamus and neuroendocrine disordersSECTION 15 Structural disorders of the hypothalamo-pituitary region2. Pituitary stalk interruption syndrome 3. Empty sella syndrome: Multiple endocrine disorders 4. Pituitary dysfunction after aneurysmal subarachnoidal hemorrhage5. Septo-optic dysplasia SECTION 16 Tumors of the hypothalamus6. Hypothalamic hormone-producing tumors 7. Craniopharyngiomas primarily affecting the hypothalamus SECTION 17 Neuroimmunological disorders8. The stress-axis in multiple sclerosis: Clinical, cellular, and molecular aspects 9. Neuroendocrine manifestations of Langerhans cell histiocytosis 10. Neuroendocrine manifestations of Erdheim-Chester disease11. Hypothalamitis and pituitary atrophy 12. Narcolepsy Type I as an autoimmune disorder 13. Neuromyelitis optica, aquaporin-4 antibodies, and neuroendocrine disorders14. Antibodies against the pituitary and hypothalamus in boxers15. Autoimmune diabetes insipidus SECTION 18 Drinking disorders16. Neuroimaging of central diabetes insipidus 17. Differential diagnosis of familial diabetes insipidus18. The vasopressin-aquaporin-2 pathway syndromes 19. Adipsic diabetes insipidus 20. Animal models for diabetes insipidus 21. Nocturnal enuresis in children: The role of arginine-vasopressinSECTION 19 Eating disorders22. Monogenic human obesity syndromes23. Hypothalamic microinflammation 24. Glucose and fat sensing in the human hypothalamus 25. Hypothalamus and neuroendocrine diseases: The use of human-induced pluripotent stem cells for disease modeling 26. Prader-Willi syndrome: Hormone therapies27. Transcriptomics of the Prader-Willi syndrome hypothalamus 28. Disorders of hypothalamic function: Insights from Prader-Willi syndrome and the effects of craniopharyngioma 29. Animal models for Prader-Willi syndrome 30. Is there a hypothalamic basis for anorexia nervosa? SECTION 20 Reproduction, olfaction and sexual behavior31. Sexual differentiation of the human hypothalamus: Relationship to gender identity and sexual orientation32. Klinefelter syndrome or testicular dysgenesis: Genetics, endocrinology, and neuropsychology33. Neurobiology of puberty and its disorders
