This detailed volume features techniques to explore the complex interface that separates the systemic circulation from the central nervous system, known as the blood-brain barrier (BBB). Beginning with an introduction to its physiology, the book continues with sections on using pluripotent stem cells in models of the BBB, co-culture, permeability and transwell models, microfluidic and chip models, as well as models to study specific BBB pathologies. Written for the highly successful
Methods in Molecular Biology
series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical,
The Blood-Brain Barrier: Methods and Protocols
collects a wide range of methodologies which will aid all researchers in the fascinating world of the blood-brain barrier.
Reihe
Sprache
Verlagsort
Verlagsgruppe
Illustrationen
73
10 s/w Abbildungen, 73 farbige Abbildungen
XI, 357 p. 83 illus., 73 illus. in color.
Dateigröße
ISBN-13
978-1-0716-2289-6 (9781071622896)
DOI
10.1007/978-1-0716-2289-6
Schweitzer Klassifikation