1 History of Regenerative Medicine, Raymund E. Horch, Laurentiu M. Popescu, and Elias Polykandriotis.- Part I Biology of tissue regeneration: 2 Extracellular Matrix and Tissue Regeneration, Yrjö T. Konttinen et al.- 3 Stem Cell Niche, Pei Wen, Pei Sun and Rongwen Xi.- 4 Stem Cells and Asymmetric Cell Division, Frank Hirth.- 5 Stem Cells in the Developing and Adult Nervous System, Fumitaka Osakada and Masayo Takahashi.- Part II Stem cell science and technology: 6 Characterization and Classifi cation of Stem Cells, Andreas Bosio, Ute Bissels and Stefan Miltenyi.- 7 Human Embryonic Stem Cells, Mikael C.O. Englund, Peter Sartipy, Johan Hyllner.- 8 Induced Pluripotent Stem Cells, Kazutoshi Takahashi and Shinya Yamanaka.- 9 Generation of Germline-Derived Stem Cells from the Adult Human Testis, Thomas Skutella and Sabine Conrad.- 10 Hematopoietic Stem Cells, Jonathan Frampton.- 11 Cardiovascular Stem Cells, Christoph Brenner, Robert David and Wolfgang-Michael Franz.- 12 Cardiac Stem Cells: Tales, Mysteries and Promises in Heart Generation and Regeneration, Maurizio Pesce, Giulio Pompilio , Elisa Gambini, Maurizio C. Capogrossi.- 13 Neural Stem Cells, Yoko Arai, Wieland B. Huttner and Federico Calegari.- 14 Liver Stem Cells, Tohru Itoh, Minoru Tanaka, and Atsushi Miyajima.- 15 Cancer Stem Cells, Murali MS Balla, Anjali P. Kusumbe, Geeta K. Vemuganti and Sharmila A. Bapat.- 16 Mesenchymal Stem Cells: An Oversimplifi ed Nomenclature for Extremely Heterogeneous Progenitors, Patrick Wuchter, Wolfgang Wagner, Anthony D. Ho.- 17 Musculoskeletal Stem Cells, Gerben M. van Buul and Gerjo J.V.M. van Osch.- Part III Tissue Engineering, Biomaterials and Nanotechnology: 18 Vector Technology and Cell Targeting: Peptide-Tagged Adenoviral Vectors as a Powerful Tool for Cell Specifi c Targeting, B.M. Pützer and A. Schmidt.- 19 Regenerative Chimerism Bioengineered Through Stem Cell Reprogramming, Timothy J. Nelson, AlmudenaMartinez-Fernandez and Satsuki Yamada.- 20 Biodegradable Materials, Michael Schroeter, Britt Wildemann, Andreas Lendlein, Andre Terzic.- 21 Functionalized Nanomaterials, Jie Zhou, Wenzhong Li, Changyou Gao.- 22 Biointerface technology, Joachim Rychly.- Part IV Regenerative Therapies: 23 Blood, Michael Schmitt and Mathias Freund.- 24 Regenerative Medicine in the Central Nervous System: Stem Cell-Based Gene-Therapy, Seung U. Kim.- 25 Regenerative Therapy for Central Nervous System Trauma, K.K. Jain.- 26 Regenerative Therapies for the Ocular Surface, Geeta K. Vemuganti, Virender S. Sangwan, Indumathi Marriappan and Dorairajan Balasubramanian.- 27 The Development of a Stem Cell Therapy for Deafness, Nopporn Jongkamonwiwat and Marcelo N. Rivolta.- 28 Dental, Kristina Arvidson, Sølve Hellem and Kamal Mustafa.- 29 Trachea, Silvia Baiguera and Paolo Macchiarini.- 30 Lung, Lavinia Coltan and Bernard Thébaud.- 31 Vascular Regeneration: Endothelial Progenitor Cell Therapy for Ischemic Diseases, Atsuhiko Kawamoto, Masaaki Ii and Takayuki Asahara.- 32 Heart, Gustav Steinhoff and Bodo Eckehard Strauer.- 33 Liver, Amar Deep Sharma, Razvan Iacob, Michael Bock, Tobias Cantz, Michael P. Manns and Michael Ott.- 34 Kidney, Hermann Haller and Sajoscha A. Sorrentino.- 35 Skin, Hans-Günther Machens, Christina Irene Günter, and Augustinus Bader.- 36 Preclinical Animal Models for Segmental Bone Defect Research and Tissue Engineering, Johannes C. Reichert, A. Berner, Siamak Saifzadeh, Dietmar W. Hutmacher.- 37 Constraints to Articular Cartilage Regeneration, Georg N. Duda, Joshua O. Eniwumide, and Michael Sittinger.- 38 Muscle and Ligament Regeneration, Thomas Mittlmeier and Ioannis Stratos.- Part V Regulation and Ethics: 39 Regulatory Frameworks for Cell and Tissue Based Therapies in Europe and the USA, Gudrun Tiedemann and Sebastian Sethe.- 40 Ethics and Law in Regenerative Medicine: A Legal and Ethical Outline on RegenerativeMedicine in Research in France, Germany and Poland, Gregor Becker and Anna Grabinski.- 41 Patient Propositions: $9.6 Billion of Medical Research Funding, Robert N. Klein II.- Index