Arsenic

Section I: Fundamentals of Arsenic Exposure and Metabolism
Chapter 1: History of Arsenic as a Poison and Medicinal 4
Chapter 2: Geogenic and Anthropogenic Arsenic Hazard in Groundwaters and Soils - Distribution, Nature, Origin & Human Exposure Routes 34
Chapter 3: Remediation of Arsenic in Drinking Water 115
Chapter 4: The Chemistry and Metabolism of Arsenic 149
Section II: Epidemiology and Disease Manifestations of Arsenic Exposure
Chapter 5: Human Population Studies and Nutritional Intervention 203
Chapter 6: Skin manifestations of chronic arsenicosis 230
Chapter 7: Lung cancer and other pulmonary diseases 247
Chapter 8: Bladder Cancer and Arsenic 300
Chapter 9: Neurological Effects of Arsenic Exposure 342
Chapter 10: Diabetes Mellitus 387
Chapter 11: Hepatotoxicity 428
Chapter 12: Genetic Epidemiology of Susceptibility to Arsenic-induced Diseases 457
Section III. Mechanisms of Toxicity
Chapter 13: Arsenic Interaction with Zinc Finger Motifs 501
Chapter 14: Role In Chemotherapy 545
Chapter 15: Genotoxicity 607
Chapter 16: Arsenic and Signal Transduction 650
Chapter 17: Stem Cell Targeting and Alteration by Arsenic 704
Chapter 18: Epigenetics and Arsenic Toxicity 748
Section IV: Models for Arsenic Toxicology, Risk Assessment
Chapter 19: Cancer Induced by Exposure to Arsenicals in Animals 779
Chapter 20: Arsenic induced cardiovascular disease 804
Chapter 21: Invertebrate Models in Arsenic Research: Past, Present & Future 835
Chapter 22: Toxicokinetics and Pharmacokinetic Modelling of Arsenic 884
Chapter 23: Considerations for a Biologically Based Risk Assessment for Arsenic 909
Chapter 24: Translating experimental data to human populations 955