Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology.
- Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics
- Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology
- Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
ISBN-13
978-0-12-809694-9 (9780128096949)
Schweitzer Klassifikation
1. Introduction 2. Epidemiology of type 2 diabetes and dementia3. Magnitude and trajectories of Type 2 diabetes mellitus (DM)-associated cognitive dysfunction4. Brain Imaging in Diabetes 5. Cerebrospinal Fluid and Blood-Based Biomarkers in Alzheimer's Disease and Type 2 Diabetes Spectrum Disorders6. Neuropathologic insights into diabetes 7. Diet, obesity, exercise, metabolism and brain8. The role of insulin resistance and signalling in dementia9. Advanced Glycation, Diabetes and Dementia 10. Neuroinflammation, Type 2 Diabetes and Dementia11. The blood-brain barrier in diabetes mellitus12. Pharmacological and non-pharmacological interventions for cognitive impairment and dementia related to type 2 diabetes and metabolic disturbances in aging
