Although many pursue understanding of the relationship between protein structure and function for the thrill of pure science, the pay-off in a much broader sense is the ability to manipulate the Earth's chemistry and biology to improve the quality of life for mankind. Immediately goals of this area of research include identification of the life-supporting functions of proteins, and the fundamental forces that facilitate these functions. Upon reaching these goals, we shall have the understanding to direct and the tools required to implement changes that will dramatically improve the quality of life. For example, under standing the chemical mechanism of diseases will facilitate development of new therapeutic drugs. Likewise, understanding of chemical mechanisms of plant growth will be used with biotechnology to improve food production under adverse climatic conditions. The challenge to understand details of protein structure/function relationships is enormous and requires an international effort for success. To direct the chemistry and biology of our environment in a positive sense will require efforts from bright, imaginative scientists located throughout the world. Although the emergence of FAX, e-mail, and the World Wide Web has revolutionized international communication, there remains a need for scientists located in distant parts of the world to occasionally meet face to face.
Sprache
Verlagsort
Verlagsgruppe
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Dateigröße
ISBN-13
978-1-4613-0359-6 (9781461303596)
DOI
10.1007/978-1-4613-0359-6
Schweitzer Klassifikation
1. How Is the Dioxygen-Iron Bond Manipulated by Transport and Catalytic Haem Proteins?.- 2. A New Flow Modulated Continuous Bioreactor Based on Inversed Capillary Membranes for Low Risk Gene Technology.- 3. Characterization and Substrate Specificities of Various Mouse Kallikreins.- 4. Natural Occurence of Enzymes Linked to Inorganic Supports: Venice Lagoon and Internal City Canals.- 5. New Developments on Human Milk Protein Composition and Function: Human Milk as a Model for the Production of Dietetic Milks.- 6. Structure-Function of Two Membrane Protein Systems Involved in Transfer of Electrical Charge.- 7. ?,?-Crystallins: Modular Building Blocks of the Eye Lens.- 8. The Use of Metal Ions as Spectroscopic Probes in the Elucidation of pKa's of Small Molecules.- 9. Trypsin Complexed with ?1-Proteinase Inhibitor Has an Increased Structural Flexibility.- 10. Structures and Functions of Leginsulin and Leginsulin-Binding Protein.- 11. From Structure to Therapy?.- 12. New Insights into the Molecular Structure of the Agonists Binding Site of Protein Kinase C by Pseudoreceptor Modeling.- 13. The Use of Synchrotron Radiation in Protein Crystallography.- 14. NMR Approaches to the Study of Structure-Function Relationships in Iron-Sulfur Proteins: Rubredoxin, [2Fe-2s] Ferredoxins, and a Rieske Protein.- 15. Thermodynamic Views of Inhibition, Activation and Denaturation of Adenosine Deaminase by Ring Opened Nucleosides and Denaturants.- 16. Domain Motions in Protein Crystals.- 17. Interaction of Bovine Serum Albumin and Hexadecyl Pyridinium Bromide Study by Surfactant Selective Electrode and Spectrophotometry.- 18. Ciliate Telomere Proteins.- 19. Diverse Actions of Human Lipoproteins on Arachidonic Acid Metabolism.- 20. Mechanism of Gonadotrophin Releasing Hormone ReceptorMediated Regulation of G-Proteins in Clonal Pituitary Gonadotrophs.- 21. Structural Studies of Carcinoembryonic Antigen (CEA) and Anti-CEA Engineered Antibodies Using Mass Spectrometry.- 22. Serotoninergic Neurones in the Zona Incerta Exerts Inhibitory Control on Gonadotrophin Release Via 5-HT2A/2C Receptors.- 23. Structure Elucidation of Human Lens Proteins by Mass Spectrometry.- 24. Isolation, Characterization and Amino Acid Sequence of the N-Terminal Functional Unit from the Rapana thomasiana grosse (Marine Snail, Gastropod) Hemocyanin.- 25. Potential Applications of Plant Glycohydrolases for Oligosaccharide Synthesis.- 26. Two-Dimensional Electrophoresis and Automated Microsequencing: Introduction and Overview.- Posters.
