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This book provides a comprehensive exploration of the role antioxidants play in preventing and managing a variety of diseases and critically examines current research on the effects of nutritional antioxidants on specific disease states.
Antioxidants: Nature's Defense Against Disease investigates the complex relationship between oxidative stress and many health disorders, providing essential insights into the role of antioxidants in disease prevention. It investigates how oxidative stress, induced by an imbalance of free radicals and antioxidants in the body, leads to the development and progression of maladies ranging from cardiovascular disorders to neurological diseases. The book includes evidence-based ways for harnessing antioxidants from natural sources such as fruits, vegetables, and herbs to reduce the impact of oxidative damage and improve general health.
The book presents the most recent scientific advances and clinical findings in antioxidant therapy. It is a comprehensive resource for healthcare professionals and researchers and covers everything from the molecular mechanisms that underpin oxidative stress to the protective benefits of antioxidants against chronic diseases. Through its interdisciplinary approach and practical insights, Antioxidants: Nature's Defense Against Disease provides readers with the knowledge and tools they need to optimize antioxidant consumption, empowering them to control their health and lower their risk of severe diseases.
Audience The core audiences for this book are nutritionists, dieticians, researchers, and graduate students in health sciences, and those interested in preventive healthcare, such as health, nutrition, fitness, and wellness enthusiasts, looking to deepen their understanding of implementing antioxidant strategies and improving lifestyle choices.
Rakesh K. Sindhu, PhD, is a professor and research and development coordinator, the School of Pharmacy, Sharda University, Greater Noida, Uttar Pradesh, India. He has published 8 books and 25 book chapters, more than 90 papers in reputed journals, and presented papers at 10 international and 30 national conferences. His research focuses on the pharmacological evaluation of herbal drugs/products, nanoformulation development and evaluation, standardization of herbal products, and phytochemical screening.
Inderbir Singh, PhD, is a professor at Chitkara College of Pharmacy, Chitkara University, Patiala, Punjab, and has a total experience of 22 years in both industry and academia. He has published more than 135 research/review articles in national and international journals, 8 books, 22 book chapters, 12 patents granted, 11 patents (applied), and 14 design registrations (applied). His research interests include neurodevelopmental disorders, gastroretentive drug delivery systems, co-processed excipients, co-crystals, biopolymers/ biomaterials/modified polymers in drug delivery, QbD, SeDeM expert system, 3D printing technology.
M. Arockia Babu, PhD, is the director of the Institute of Pharmaceutical Research, GLA University, Mathura, Chaumuhan, Uttar Pradesh, India. He has more than 23 years of expertise in administration and research and has lectured extensively around the world.
Preface xxiii
1 Basics of Antioxidants and Their Importance 1Shuchi Goyal, Divya Thirumal, Sumitra Singh, Dinesh Kumar, Inderbir Singh, Gautam Kumar and Rakesh K. Sindhu
2 Antioxidants in Cancer Prevention 21Asad Ur Rahman and Pharkphoom Panichayupakaranant
3 Antioxidants in Inflammatory Diseases 83Sayed Mohammed Firdous, Sourav Pal, Subhajit Mandal and Rakesh K. Sindhu
4 Antioxidants in Cardiovascular Disease: Molecular Interaction and Therapeutic Implications 127Sayed Mohammed Firdous and Sourav Pal
5 Antioxidant Therapy: A Promising Avenue for Regulating Inflammation in Psoriasis 153Seema Joshi and Dharmesh Trivedi
6 Antioxidants in Infectious Disease Management 169Kenneth C. Ugoeze and Oluwatoyin A. Odeku
7 Role of Antioxidant Therapy in Respiratory Disease Management 219Bidisha Bhattacharya, Naina Devi, Sanshita, Ameya Sharma, Vivek Puri, Sandeep Kumar, Rakesh K. Sindhu and Inderbir Singh
8 Antioxidants in Aging 257Harpreet Singh, Sourav Mohanto, Adrija Bhunia, Bhuvnesh Kumar Singh, Kanupriya Chauhan, Arvind Kumar, Amrita Mishra, Arun Kumar Mishra and Alankar Shrivastav
9 Antioxidants Against Neurological Disorders 285Jasjeet Kaur Narang, Anmol Dogra, Tajpreet Kaur, Ramandeep Singh Narang and Amrit Pal Singh
10 Role of Antioxidants for the Treatment of Metabolic Disorders 369Sanshita, Mayank Sharma, Payal Dande, Piyush Ghode, Atul A. Shirkhedkar, Amit Chaudhary and Inderbir Singh
11 Hepatoprotective Potential of Antioxidants in Medicinal Plants 411Sayed Mohammed Firdous, Sahabaj Ali Khan and Amritangshu Maity
12 Antioxidant Effects of Medicinal Plants for the Treatment of Epilepsy 441Sayed Mohammed Firdous, Shouvik Mallik and Bijoy Paria
13 Antioxidants and Obesity 491Parul Sood, Gagandeep Kaur, Komal Thapa, Kiran Sharma and Rakesh K. Sindhu
14 Antioxidants in Hypertension 511Bharath Harohalli Byregowda, Farmiza Begum, Chaman Bala, Yogendra Nayak, Rakesh K. Sindhu and Gautam Kumar
15 Antioxidants and Rheumatoid Arthritis 537Chaman Bala, Bharath Harohalli Byregowda, Farmiza Begum, Yogendra Nayak, Rakesh K. Sindhu and Gautam Kumar
16 Antioxidants in Skin Disorders 551Satyender Kumar, Dil Prasad Subba, Seema, Sayed Mohammed Firdous, Oluwatoyin A. Odeku, Sandeep Kumar and Rakesh K. Sindhu
17 Antioxidants and Toxicity 573Ritu Sanwal, Vichitra Kaushik, Brijendra Singh, Nittan Kumar and Atul Kaushik
18 Exploring the Therapeutic and Pharmaceutical Potential of Antioxidants 587Sumanta Bhattacharya
19 Regulatory Aspects of Antioxidants 613Kiran Kumar Bellapu, Tejaswini Mergu, Nikhil Vinod Shirsath, Pooja Anil Shende, Pavankumar Yashvantrao Vasu, Deepak Jindal, Parul Grover, Saurabh Srivastava, Rakesh K. Sindhu and Sandeep Kumar
Index 629
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