Venous Ulcers, Second Edition, provides a comprehensive synthesis of evidence-based recommendations and the highest level of expertise from a leading group of doctors, which is a fundamental constituent for the appropriate management of nonhealing venous wounds in everyday practice. This book offers a fertile environment for a complete understanding of genetics and molecular and biochemical mechanisms that lead to the development and progression of venous ulcers, which is essential for elucidating the underlying pathophysiology and can be utilized for developing novel therapies and accessing previously inaccessible areas of research. Socioeconomic impact, impact on health-related quality of life, the clinical course of the disease, and diagnostic algorithms are elaborated in detail. All currently available treatment modalities are explained in a clinically applicable approach with particular emphasis on operative technique, technical feasibility, success rates (both clinical and technical), and side effects. Lastly, this book elaborates on special diagnostic considerations and management of the most complex patients, often requiring the highest level of expertise for successful treatment.
- Provides a detailed understanding of molecular mechanisms that lead to venous ulcerations that can provide a fertile environment for scientists for further discoveries
- Summarizes new findings on etiology, hemodynamics, pathophysiology, diagnosis, and treatment of patients with venous ulcers
- Discusses all currently utilized diagnostic and treatment modalities, as well as provides clear guidelines pertinent to special diagnostic considerations in a clinically applicable approach
Auflage
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-323-98587-1 (9780323985871)
Schweitzer Klassifikation
Section 1: Chronic venous insufficiency - basic considerations 1. Pathophysiology of chronic venous disease: genetic, molecular and biochemical mechanisms2. Venous hemodynamics and microcirculation in chronic venous insufficiency3. Venous ulcers of the lower extremity: etiology, risks and predictive factors4. Venous ulcers of the lower extremity: epidemiology and socio-economic burden
Section 2: Clinical evaluation and diagnostic modalities5. Initial clinical evaluation in patients with chronic venous insufficiency6. Ultrasound evaluation of lower extremity chronic venous disease7. The diagnosis of major venous outflow obstruction in chronic venous insufficiency8. Hypercoagulable states associated with chronic venous insufficiency9. The chronically swollen leg with ulcers - finding the cause: theory and practice10. Lower extremity wounds associated with mixed venous and arterial insufficiency and relevant differential diagnosis11. Assessment tools and wound documentation for patients with chronic venous insufficiency
Section 3: Non-operative management of chronic venous insufficiency and wound care12. Compression therapy in venous leg ulcers13. Wound healing: adjuvant therapy and treatment adherence14. Negative pressure wound healing for venous ulcers15. Medical therapies for chronic venous insufficiency16. Treatment modalities for the management of nonhealing wounds in patients with chronic venous insufficiency17. Deep vein thrombosis and prevention of postthrombotic syndrome18. Improving treatment outcomes - management of coexisting comorbidities in patients with venous ulcers19. Emerging modalities in local treatment of venous ulcers: advanced dressings, bioengineering, and biologics
Section 4: Operative and endovascular procedures for chronic venous insufficiency20. Benefits of superficial venous intervention (surgery or endovenous ablation) in the treatment of venous leg ulceration21. Superficial surgery and perforator interruption in the treatment of venous leg ulcers22. Endovascular techniques for superficial vein ablation in treatment of venous ulcers23. Treatment of chronic venous insufficiency with foam sclerotherapy24. Ultrasound guidance for endovenous treatment25. Iliac vein stenting in venous leg ulcers26. Venous valve reconstructions in patients with severe chronic venous insufficiency
Section 5: Special considerations27. Treatment of recalcitrant venous ulcers with free tissue transfer for limb salvage28. Management of venous ulcers in patients with congenital vascular malformations29. Lymphatic disorders in pathogenesis of chronic venous insufficiency
