Today, as the large international genome sequence projects are gaining a great amount of public attention and huge sequence data bases are created it be comes more and more obvious that we are very limited in our ability to access functional data for the gene products -the proteins, in particular for enzymes. Those data are inherently very difficult to collect, interpret and standardize as they are highly distributed among journals from different fields and are often sub ject to experimental conditions. Nevertheless a systematic collection is essential for our interpretation of the genome information and more so for possible appli cations of that knowledge in the fields of medicine, agriculture, etc .. Recent pro gress on enzyme immobilization, enzyme production, enzyme inhibition, coen zyme regeneration and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. It is the functional profile of an enzyme that enables a biologist of physician to analyze a metabolic pathway and its disturbance; it is the substrate specificity of an enzyme which tells an analytical biochemist how to design an assay; it is the stability, specificity and efficiency of an enzyme which determines its usefulness in the biotechnical transformation of a molecule. And the sum of all these data will have to be considered when the designer of artificial biocatalysts has to choose the optimum prototype to start with.
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ISBN-13
978-3-642-59025-2 (9783642590252)
DOI
10.1007/978-3-642-59025-2
Schweitzer Klassifikation
6-Phosphofructo-2-kinase.- Glucose-1,6-bisphosphate synthase.- Diacylglycerol kinase.- Dolichol kinase.- [Hydroxymethylglutaryl-CoA reductase (NADPH)] kinase.- Dephospho-[reductase kinase] kinase.- Protein-tyrosine kinase.- Deoxyguanosine kinase.- AMP-thymidine kinase.- [3-Methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase.- [Isocitrate dehydrogenase (NADP+)] kinase.- Myosin-light-chain kinase.- ADP-thymidine kinase.- Hygromycin-B kinase.- Caldesmon kinase.- Phosphoenolpyruvate-glycerone phosphotransferase.- Xylitol kinase.- Ca2+/calmodulin-dependent protein kinase.- [Tyrosine 3-monooxygenase] kinase.- Rhodopsin kinase.- beta-Adrenergic-receptor kinase.- 1D-myo-Inositol-trisphosphate 3-kinase.- [Acetyl-CoA carboxylase] kinase.- Myosin-heavy-chain kinase.- Tetraacyldisaccharide 4'-kinase.- Low-density-lipoprotein kinase.- Tropomyosin kinase.- 1D-myo-Inositol-trisphosphate 6-kinase.- 1D-myo-Inositol-tetrakisphosphate 1-kinase.- Tau-protein kinase.- Macrolide 2'-kinase.- 1-Phosphatidylinositol 3-kinase.- Ceramide kinase.- 1D-myo-Inositol-trisphosphate 5-kinase.- 1D-myo-Inositol-tertrakisphosphate 5-kinase.- [RNA-polymerase]-subunit kinase.- Glycerol-3-phosphate-glucose phosphotransferase.- Acetate kinase.- Carbamate kinase.- Phosphoglycerate kinase.- Aspartate kinase.- Formate kinase.- Butyrate kinase.- Acetylglutamate kinase.- Phosphoglycerate kinase (GTP).- Glutamate 5-kinase.- Acetate kinase (pyrophosphate).- Glutamate 1-kinase.- Branched-chain-fatty-acid kinase.- Guanidinoacetate kinase.- Creatine kinase.- Arginine kinase.- Taurocyamine kinase.- Lombricine kinase.- Hypotaurocyamine kinase.- Opheline kinase.- Ammonia kinase.- Phosphoenolpyruvate-protein phosphotransferase.- Agmatine kinase.- Protein-histidine pros-kinase.- Protein-histidine tele-kinase.-Polyphosphate kinase.- Phosphomevalonate kinase.- Adenylate kinase.- Nucleoside-phosphate kinase.- Nucleoside-diphosphate kinase.- Phosphomethylpyrimidine kinase.- Guanylate kinase.- dTMP kinase.- Nucleoside-triphosphate-adenylate kinase.- (Deoxy)adenylate kinase.- T2-induced deoxynucleotide kinase.- (Deoxy)nucleoside-phosphate kinase.- Cytidylate kinase.- Thiamine-diphosphate kinase.- Thiamine-phosphate kinase.- 3-Phosphoglyceroyl-phosphate-polyphosphate phosphotransferase.- Farnesyl-diphosphate kinase.- 5-Methyldeoxycytidine-5'-phosphate kinase.- Dolichyl-diphosphate-polyphosphate phosphotransferase.- Ribose-phosphate pyrophosphokinase.- Thiamine pyrophosphokinase.- 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.- Nucleotide pyrophosphokinase.- GTP pyrophosphokinase.- Nicotinamide-nucleotide adenylyltransferase.- FMN adenylyltransferase.- Pantetheine-phosphate adenylyltransferase.- Sulfate adenylyltransferase.- Sulfate adenylyltransferase (ADP).- DNA-directed RNA polymerase.- DNA-directed DNA polymerase.- Polyribonucleotide nucleotidyltransferase.- UTP-glucose-1-phosphate uridylyltransferase.- UTP-hexose-1-phosphate uridylyltransferase.- UTP-xylose-1-phosphate uridylyltransferase.- UDPglucose-hexose-1-phosphate uridylyltransferase.- Mannose-1-phosphate guanylyltransferase.- Ethanolamine-phosphate cytidylyltransferase.- Choline-phosphate cytidylyltransferase.- Nicotinate-nucleotide adenylyltransferase.- Polynucleotide adenylyltransferase.- tRNA cytidylyltransferase.- Mannose-1-phosphate guanylyltransferase (GDP).- UDP-N-acetylglucosamine pyrophosphorylase.- Glucose-1-phosphate thymidylyltransferase.- tRNA adenylyltransferase.- Glucose-1-phosphate adenylyltransferase.- Nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase.-Hexose-1-phosphate guanylyltransferase.- Fucose-1-phosphate guanylyltransferase.- DNA nucleotidylexotransferase.- Galactose-1-phosphate thymidylyltransferase.- Glucose-1-phosphate cytidylyltransferase.- Glucose-1-phosphate guanylyltransferase.- Ribose-5-phosphate adenylyltransferase.- Aldose-1-phosphate adenylyltransferase.- Aldose-1-phosphate nucleotidyltransferase.- 3-Deoxy-manno-octulosonate cytidylyltransferase.- Glycerol-3-phosphate cytidylyltransferase.- D-Ribitol-5-phosphate cytidylyltransferase.- Phosphatidate cytidylyltransferase.- [Glutamate-ammonia-ligase] adenylyltransferase.- N-Acylneuraminate cytidylyltransferase.- Glucuronate-1-phosphate uridylyltransferase.- Guanosine-triphosphate guanylyltransferase.- Gentamicin 2"-nucleotidyltransferase.- Streptomycin 3"-adenylyltransferase.- RNA-directed RNA polymerase.- RNA-directed DNA polymerase.- mRNA guanylyltransferase.- Adenylylsulfate-ammonia adenylyltransferase.- RNA uridylyltransferase.- ATP adenylyltransferase.- Phenylalanine adenylyltransferase.- Anthranilate adenylyltransferase.- tRNA nucleotidyltransferase.- N-Methylphosphoethanolamine cytidylyltransferase.- (2,3-Dihydroxybenzoyl)adenylate synthase.- Ethanolaminephosphotransferase.- Diacylglycerol cholinephosphotransferase.- Ceramide cholinephosphotransferase.- Serine-phosphoethanolamine synthase.- CDPdiacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase.- Undecaprenyl-phosphate galactosephosphotransferase.- Holo-[acyl-carrier-protein] synthase.- CDPdiacylglycerol-serine O-phosphatidyltransferase.- Phosphomannan mannosephosphotransferase.- Sphingosine cholinephosphotransferase.- CDPdiacylglycerol-inositol 3-phosphatidyltransferase.- CDPglycerol glycerophosphotransferase.- Phospho-N-acetylmuramoyl-pentapeptide-transferase.- CDPribitolribitolphosphotransferase.- UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase.- UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase.- UDPgalactose-UDP-N-acetylglucosamine galactosephosphotransferase.- UDPglucose-glycoprotein glucosephosphotransferase.- Phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase.- Membrane-oligosaccharide glycerophosphotransferase.- 1-Alkenyl-2-acylglycerol cholinephosphotransferase.- Pyruvate,orthophosphate dikinase.- Pyruvate,water dikinase.- Thiosulfate sulfurtransferase.- 3-Mercaptopyruvate sulfurtransferase.- Thiosulfate-thiol sulfurtransferase.- tRNA sulfurtransferase.- Thiosulfate-dithiol sulfurtransferase.- Aryl sulfotransferase.- Alcohol sulfotransferase.- Amine sulfotransferase.- Estrone sulfotransferase.- Chondroitin 4-sulfotransferase.- Choline sulfotransferase.- UDP-N-acetylgalactosamine-4-sulfate sulfotransferase.- Desulfoheparin sulfotransferase.- Tyrosine-ester sulfotransferase.- Renilla-luciferin sulfotransferase.- Galactosylceramide sulfotransferase.- Heparitin sulfotransferase.- Psychosine sulfotransferase.- Bile-salt sulfotransferase.- Steroid sulfotransferase.- Thiol sulfotransferase.- Chondroitin 6-sulfotransferase.- Cortisol sulfotransferase.- Triglucosylalkylacylglycerol sulfotransferase.- Protein-tyrosine sulfotransferase.- Keratan sulfotransferase.- Arylsulfate sulfotransferase.- Heparin-glucosamine 3-O-sulfotransferase.- Desulfoglucosinolate sulfotransferase.- Flavonol 3-sulfotransferase.- Quercetin-3-sulfate 3'-sulfotransferase.- Quercetin-3-sulfate 4'-sulfotransferase.- Quercetin-3,3'-bissulfate 7-sulfotransferase.- Propionate CoA-transferase.- Oxalate CoA-transferase.- Malonate CoA-transferase.- 3-Oxoacid CoA-transferase.-3-Oxoadipate CoA-transferase.- Succinate-citramalate CoA-transferase.- Acetate CoA-transferase.- Butyrate-acetoacetate CoA-transferase.- Citrate-CoA transferase.- Citramalate CoA-transferase.- Glutaconate CoA-transferase.- Succinate-hydroxymethylglutarate CoA-transferase.- 5-Hydroxypentanoate CoA-transferase.
