Glycobiology of the Nervous System

1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates..- 2. Introduction to cells comprising the nervous system..- 3. Synthesis.- processing.- and function of N-glycans in N-glycoproteins..- 4. Synthesis of O-linked glycoconjugates in the nervous system..- 5. Chemistry and function of glycosaminoglycans in the nervous system..- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system..- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics..- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR..- 9. Glycolipid and glycoprotein expression during neural development..- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide)..- 11. Role of myelin-associated glycoproteins in the peripheral nervous system..- 12. Glycosignaling: a general review..- 13. Glycosphingolipids in the regulation of the nervous system..- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration..- 15. Glycoconjugates in nuclear membranes..- 16. N-glycosylation in regulation of the nervous system..- 17. Role of carbohydrates in the interaction of pathogens with neural cells..- 18. Glycoconjugate changes in aging and age-related diseases..- 19. Gangliosides and glycolipids in neurodegenerative disorders..- 20. Inborn errors of glycosphingolipid catabolism and potential treatment..- 21. Neurological aspects of human glycosylation disorders..- 22. Glycoconjugates and neural tumors..- 23. Galectins and neuroinflammation ..- 24. Glycoconjugates and neuroimmunological diseases..- 25. Targeting nanoparticle drug carriers to the brain..- 26. Use of quantum dots to treat inherited lysosomal storage diseases..- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates.