Neurobiology of Abnormal Emotion and Motivated Behaviors: Integrating Animal and Human Research pulls together world-renowned leaders from both animal and human research, providing a conceptual framework on how neuroscience can inform our understanding of emotion and motivation, while also outlining methodological commonalities between animal and human neuroscience research, with an emphasis on experimental design, physiological recording techniques and outcome measures. Typically, researchers investigating the neurobiology of emotions focus on either animal models or humans. This book brings the two disciplines together to share information and collaborate on future experimental techniques, physiological measures and clinical outcomes.
- Integrates animal and human research to aid readers in discovering a clear path forward for translating basic science to clinical applications
- Provides overviews of the most recent research into the neuroscience behind maladaptive behaviors and psychiatric disorders
- Explores the commonalities in methods and outcome measures between animal and human researchers and how those commonalities can be harnessed for future collaboration and translational work
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
ISBN-13
978-0-12-813694-2 (9780128136942)
Schweitzer Klassifikation
Introduction: Emotion and Motivated Behaviors: Integrating Animal and Human Neurobiology Research
Section 1: Emotion-related impulsivity across disorders and species1. Impulsive traits give rise to a wide range of maladaptive behaviors2. Methods to develop a preclinical model of negative urgency3. Mood-related impulsivity in the onset and course of mood disorders
Section 2: Impulsivity and stress in eating disorders4. Trait impulsivity, stress reactivity, and disordered eating behavior5. Etiology of eating disorders with an emphasis on genetic and neurobiological risk factors6. Anorexic behavior7. Eating disorders
Section 3: Interaction of stress and drug-seeking8. Human bio-behavioral data delineating stress system sensitization as well as cognitive and emotional dysregulation during early abstinence from alcohol and cocaine9. Interactions between stress- and drug-seeking behaviors10. Synaptic mechanisms of the behavioral effects of alcohol
Section 4: Learning to inhibit the fear response11. Insular and prefrontal cortex in aspects of stress mitigation, fear learning, and drug seeking12. How anxiety affects social behaviors13. Neural mechanisms of fear relapse14. Overgeneralization of the fear response to stimuli that have never been associated with an aversive outcome
Section 5: Abnormal emotional reactivity versus regulation across disorders15. Common affective symptoms that manifest in depression and schizophrenia16. Abnormal processing of emotional information in major depression17. Deficits in attention, cognitive control, and emotion regulation in schizophrenia18. Cognitive impairment and affective deficits across depression and schizophrenia
