Autophagy in Health and Disease

Section I - Overview1. IntroductionBeverly A. Rothermel and Abhinav Diwan2. Mechanisms of autophagy: the machinery of macroautophagy and points of controlCongcong He3. Regulation of autophagy - transcriptional, posttranscriptional, translational, and posttranslational mechanismsLogan Slade and Thomas Pulinilkunnil4. Selectivity and trafficking of autophagic cargoesNuzhat Ahsan, Kautilya Kumar Jena, Subhash5. The role of lysosomes in autophagyYoana Rabanal-Ruiz and Viktor I. Korolchuk6. Methods for measuring autophagyAllen Andres7. Effects of physiologic inputs on autophagyTobias Eisenberg, Mahmoud Abdellatif, Senka Ljubojevic-Holzer and Simon SedejSection II - Development8. Autophagy in germ cells, stem cells, and induced pluripotent stem cells Moydul Islam, Ngoc Uyen Nhi Nguyen, Abhinav Diwan and Beverly A. Rothermel9. Role of autophagy in embryogenesisTakayuki Tatsumi and Satoshi Tsukamoto10. Autophagy in hematopoiesis and leukemogenesisAngela Ianniciello and G. Vignir Helgason11. Autophagy in cell plasticity with particular focus on paligenosisMegan D. Radyk, Lillian B. Spatz and Jason C. MillsSection III - Metabolic control and diabetes12. Autophagy in the liverMark Li and Ling Yang13. Autophagy in adipose tissueVishaka Vinod and Sihem Boudina14. Autophagy in the pancreasAmelia Williams, Merilin Georgiou and Catherine Arden15. Skeletal muscleGreg R. Markby and Kei SakamotoSection IV - Cardiovascular System16. Autophagy in the cardiovascular systemDaniel Peñ-Oyarzún, Valeria Garrido-Moreno, Luis Garrido-Olivares, Ramon Corbalan, Alfredo Criollo and Sergio Lavandero17. LungsPoornima Mahavadi, Martina Korfei and Andreas Guenther18. Autophagy in the vasculatureBieke Steenput, Cédric HG. Neutel, Nina Hermans, Wim Martinet, Guido R.Y. De Meyer, Pieter-Jan Guns and Lynn RothSection V - The nervous system and neurodegeneration19. Altered autophagy on the path to Parkinson's diseaseIrene Sanchez-Mirasierra, Sergio Hernandez-Diaz, Saurav Ghimire, Patrick Main and Sandra-Fausia Soukup20. Autophagic processes in early- and late-onset Alzheimer's diseaseChenglong Xie, Yahyah Aman, Johannes Frank, Maria Jose Donate-Lagartos, Ruben Gudmundsrud, Katerina Cechová, Liu Shi, Martin Vyhnalek and Evandro F. FangSection VI - Homeostasis and disease in other organ systems21. Autophagy as an integral immune system componentElizabeth Bueno, Samuel Wyatt, Robyn Duttenhefner, Daniel Asa, Srinivasulu Dasanna and Sangita C. Sinha22. Autophagy in the gastrointestinal system and cross talk with microbiotaFelipe X. Pimentel-Muiños23. Role of autophagy in building and maintaining the skeletal systemOlivier Camuzard, Marie-Charlotte Trojani, Georges F. Carle and Vale¿rie Pierrefite-Carle24. Autophagy on the road to longevity and agingMaria Manifava and Nicholas T. Ktistakis25. Autophagy in cancer: friend or foe?Silvia Vega-Rubín-de-Celis26. Mammalian microautophagy: mechanism and roles in diseaseTakahiro Seki and Hiroshi Katsuki27. Chaperone-mediated autophagy - mechanisms and disease roleAmelina Albornoz, Alvaro Sequeida, Christian Rodríguez and Mauricio Budini28. Targeting autophagy: lifestyle and pharmacological approachesAlfredo Briones-Herrera, Tania Gómez-Sierra, Elena Martínez-Klimova, Belén Bellido and José Pedraza-Chaverr