Pharmacoresistance in Epilepsy

Chapter 1: Why study Drug Resistant Epilepsy?.- Chapter 2: Pharmacoresistance in Epilepsy.- Chapter 3: Experimental models for the study of drug-resistant epilepsy.- Chapter 4: On Complexity and Emergence: Linking the Hypotheses of Pharmacoresistance in Epilepsy.- Chapter 5: Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy.- Chapter 6: Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level?.- Chapter 7: Changes in Targets as an Explanation for Drug Resistance in Epilepsy.- Chapter 8: Cellular and molecular mechanisms of neuroinflammation in drug-resistant epilepsy.- Chapter 9: Contribution of the antiepileptic drug administration regime to avoid the development and/or establishment of pharmacoresistant epilepsy.- Chapter 10: Pharmacogenetics in Epilepsy and Refractory Epilepsy.- Chapter 11: Seizures Induce Hypoxia or Hypoxia Induces Seizures. A Perverse Relationship that Increases the Risk of SUDEP.- Chapter 12: Neonatal excitotoxicity triggers degenerative processes related to seizure susceptibility and pharmacoresistance.- Chapter 13: Cerebrovascular remodeling and the role of vascular endothelial growth factor in the epileptic brain and pharmacoresistance.- Chapter 14: The Role of JNK3 in Epilepsy and Neurodegeneration.- Chapter 15: Application of proteomics in the study of molecular markers in epilepsy.- Chapter 16: GABAergic neurotransmission abnormalities in pharmacoresistant epilepsy: experimental and human studies.- Chapter 17: Genes involved in pharmacoresistant epilepsy.- Chapter 18: Drug-resistant Epilepsy and the Influence of Age, Gender and Comorbid Disorders.- Chapter 19: Indications for Intracerebral Recording in Candidates for Epilepsy Surgery.- Chapter 20: On the Development of New Drugs for the Treatment of Drug Resistant Epilepsy: An Update on Different Approaches to Different Hypotheses.- Chapter 21: Physical exercise as a strategy to reduce seizure susceptibility.- Chapter 22: Ketogenic Diet and Drug-resistant Epilepsy.- Chapter 23: Modulating P-glycoprotein Regulation as a Therapeutic Strategy for Pharmacoresistant Epilepsy.- Chapter 24: Vagus Nerve Stimulation for Intractable Seizures.- Chapter 25: Non Invasive Brain Stimulation as a potential Therapeutic Procedure in drug-resistant epilepsy.- Chapter 26: Effects of transcranial focal electrical stimulation via concentric ring electrodes on seizure activity.