PrefaceSection IIMMUNOASSAY TECHNOLOGYRIA (Radioimmunoassay)1. Yalow, R.S., Berson, S.A. (1960: Assay of plasma insulin in man.FPIA (Fluorescence Polarization Immunoassay)2. Dandliker, W.B., Feigen, G.A. (1961): Quantification of the antigen-antibody reaction by the polarization of fluorescence. CPB (Competitive Protein Binding)3. Murphy, B.E.P., Pattee, C.J. (1964): Determination of thyroxine utilizing the property of protein-binding. ELISA (Enzyme-Linked Immunosorbent Assay)4. Engvall, E., Perlmann, P. (1972): Enzyme-linked immunosorbent assay, ELISA. III.EMITä (Enzyme Immunoassay Technique)5. Rubenstein, K.E., Schneider, R. S., Ullman, E.F. (1972): "Homogeneous" enzyme immunoassay. Section IITHERAPEUTIC DRUG MONITORING (TDM)Bromide6. Wuth, O. (1927): Rational bromide treatment. Sulfonamides7. Bratton, A.C., Marshall, E.K., Jr., (1939): A New Coupling Component for Sulfanilamide Determination. Quinine and Quinidine8. Brodie, B.B., Udenfriend, S. (1943): The estimation of quinine in human plasma with a note on the estimation of quinidine. Digoxin9. Smith, T.W., Butler, V.P., Haber, E. (1969): Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay. Theophylline10. Thompson, R.D., Nagasawa, H.T., Jenne, J.W. (1974): Determination of theophylline and its metabolites in human urine and serum by high-pressure liquid chromatography. Section IIIENZYMOLOGYALP (Alkaline Phosphatase, EC 3.1.3.1))11. Bessey, O.A., Lowry, O.H., Brock, M.J. (1946): A method for the rapid determination of alkaline phosphatase with five cubic millimeters of serum.AST (Aspartate Aminotransferase, EC 2.6.1.1)12. Karmen, A., Wroblewski, F., LaDue, J.S. (1955): Transaminase activity in human blood. CK (Creatine Kinase, EC 2.7.3.2) 13. Mercer, D.W. (1974): Separation of tissue and serum creatine kinase isoenzymes by ion-exchange column chromatography. Section IV SPECIFIC ANALYTES Colorimetric Analysis with the Duboscq14. Folin, O., Wu, H. (1919): A system of blood analysis. Blood Gases by Manometer15. Van Slyke, D.D. (1924): The determination of gases in blood and other solutions by vacuum extraction and manometric measurement. I. Bilirubin, Total and Direct With the Filter Photometer16. Malloy, H.T., Evelyn, K.A. (1937): The determination of bilirubin with the photometric colorimeter.Proteins by the Biuret Reaction17. Gornall, A. G., Bardawill, C. J., David, M. M. (1949): Determination of serum proteins by means of the Biuret reaction.Methods for Pediatric and Neonatal Samples18. Natelson, S. (1951): Routine use of ultramicro methods in the clinical laboratory.Enzymatic Glucose19. Huggett, A.S., Nixon, D.A. (1957): Use of glucose oxidase, peroxidase, and o-dianisidine in determination of blood and urinary glucose. HCG (Human Chorionic Gonadotropin) by Immunoassay20. Wide, L., Gemzell, C.A. (1960): An immunological pregnancy test.Hemoglobin A1c21. Rahbar, S. (1968): An Abnormal Hemoglobin in Red Cells of Diabetics. LDL (Low Density Lipoprotein) Cholesterol by Calculation22. Friedewald, W.T., Levy, R.I., Fredrickson, D.S. (1972): Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.Section V INSTRUMENTATION AND TECHNIQUESPaper Electrophoresis23. Durrum, E.L. (1950): A microelectrophoretic and microionophoretic technique. Automated Analyzer24. Skeggs, L.T. (1957): An automatic method for colorimetric analysis. Enzymatic Glucose, Dry Reagents on Pads25. Free, A.H., Adams, E.C., Kercher, M.L., Free, H. M., Cook, M. H., (1957): Simple Specific Test for Urine Glucose.Blood Gas Elelctrodes26. Severinghaus, J., Bradley, A.F. (1958): Electrodes for blood pO2 and pCO2 determination. Specific Ion Electrodes27. Friedman, S.M., Nakashima, M. (1961): Single sample analysis with the sodium electrode.Centrifugal Analyzer28. Anderson, N.G. (1969): Analytical techniques for cell fractions. XII.