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Dr. Michael A. Repka is Chair and Professor of the Department of Pharmaceutics at The University of Mississippi, as well as Director of the Pii Center for Pharmaceutical Technology. Dr. Repka joined the faculty at Ole Miss after receiving his Ph.D. from The University of Texas College of Pharmacy and founded a pharmaceutical research/development company that specializes in drug delivery. His research interests include oral transmucosal and transdermal/trans-nail delivery systems, as well as other novel dosage forms. Many of these systems are directed toward the solubilization and delivery of poorly soluble bioactives via Hot Melt Extrusion technology, which is a primary focus of his research. Dr. Repka's most important scientific accomplishments involve the advancement of melt extrusion technology. He has established himself as an expert in this major pharmaceutical processing field through his numerous peer-reviewed publications, presentations and scientific talks.
Dr. Nigel Langley is currently Head of Marketing and Technical Sales at BASF Corporation where he is responsible for the promotion and technical support for BASF's Pharmaceutical excipients and APIs to the Pharmaceutical Industry in North America. He has a strong interest in solubilization including Hot Melt Extrusion. He received his PhD in Liquid Crystals from Hull University, UK and an MBA from Leeds University, UK. Prior to joining BASF he worked for Croda International in UK, Japan and USA.
Melt Extrusion in Drug Delivery: Three Decades of Progress.- Twin Screw Extrusion for Pharmaceutical Processes.- Properties and Applications of Polyvinyllactam Polymers.- Properties and Applications of Hypromellose Acetate Succinate (HPMCAS) for Solubility Enhancement Using Melt Extrusion.- Cellulose Ethers for Extrusion Applications.- Properties and Applications of Polyethylene Oxide and Ethylcellulose for Tamper Resistance and Controlled Drug Delivery.- Formulation Development of Amorphous Solid Dispersions Prepared by Melt Extrusion.- Non-Sink In Vitro Dissolution Testing of Amorphous Solid Dispersions.- Manufacture of Pharmaceutically Relevant Materials by Mechanochemistry Using Twin Screw Extrusion.- Melt Extruded Controlled Release Dosage Forms.- Excipient/API Melt Processing via Injection Molding.- Devices and Implants Prepared Using Hot Melt Extrusion.- Solid Lipid Extrusion.- Formulation, Bioavailability and Manufacturing Process Enhancement: Novel Applications of Melt Extrusion in Enabling Product Development.- Hot Melt Extrusion as a Continuous Pharmaceutical Manufacturing Process.- Hot-Melt Extrusion Process Design Using Process Analytical Technology.- Consistency of Pharmaceutical Products: An FDA Perspective on Hot-melt Extrusion Process.- Melt Extrusion: A Commercial Perception to Practicality.- Future Trends.
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