Indicator Displacement Assays (IDAs): An Innovative Molecular Sensing Approach

Name: Indicator Displacement Assays (IDAs): An Innovative Molecular Sensing Approach
Brand: De Gruyter
Price: 45.28 EUR
Availability: OnlineOnly

Ishfaq Ahmad Rather Rashid Ali(Autor*in)

De Gruyter (Verlag)

1. Auflage

Erschienen am 7. August 2024

205 Seiten

E-Book

ePUB mit Adobe-DRM

Systemvoraussetzungen

978-981-5165-91-3 (ISBN)

45,28 €inkl. 7% MwSt.

Systemvoraussetzungen

für ePUB mit Adobe-DRM

E-Book Einzellizenz

Als Download verfügbar

Beschreibung

Weitere Details

Weitere Ausgaben

Inhalt

Cover
Title
Copyright
End User License Agreement
Contents
Foreword
Preface
Background and Basic Concepts of Indicator Displacement Assays
1. INTRODUCTION
2. COMMONLY USED SYNTHETIC RECEPTORS AND INDICATORS FOR THE DESIGN OF IDAS
3. VARIOUS PHYSICAL AND CHEMICAL PHENOMENA INVOLVED IN CHEMICAL SENSING
3.1. Photoinduced Electron Transfer (PET)
3.2. Fluorescence Resonance Energy Transfer (FRET)
3.3. Charge-Transfer (CT)
3.4. Excited-State Intramolecular Proton Transfer (ESIPT)
3.5. Photon Upconversion (UC)
3.6. Aggregation-Induced Emission (AIE)
4. CLASSIFICATION OF CHEMICAL SENSORS
4.1. Electrical and Electrochemical Sensors
4.2. Thermometric Sensors
4.3. Optical Sensors
5. USEFULNESS AND APPLICATIONS OF INDICATOR DISPLACE- MENT ASSAYS
6. IDA-BASED THERMODYNAMIC EQUILIBRIUM
7. ROLE OF INTERMOLECULAR INTERACTIONS IN DESIGNING IDAS
7.1. Hydrogen Bonding (H-bonding)
7.2. Halogen Bonding
7.3. Cation-p and Anion-p Interactions
7.4. CH-p and p -p Stacking Interactions
7.5. Van Der Waals Interactions
8. DESIGN STRATEGIES OF IDAS
9. SUPRAMOLECULAR TANDEM ASSAYS
10. ADVANTAGES AND DISADVANTAGES OF IDA-BASED SENSORS
CONCLUSION
ACKNOWLEDGEMENTS
REFERENCES
Colorimetric Indicator Displacement Assays (C-IDAs)
1. INTRODUCTION
2. CHROMOGENIC SENSING ENSEMBLE
2.1. Thermodynamic Equilibrium
2.2. Molecular Design Setup and Environmental Factors
2.3. Signal Transduction Mechanism
3. CLASSIFICATION OF SENSING ENSEMBLES
3.1. Two-Component Sensing Ensembles
3.2. Three-Component Sensing Ensembles
3.3. Multicomponent Sensing Ensembles
3.4. Inorganic-Organic Hybrid Sensing Ensembles
4. C-IDA BASED ANION SENSORS
4.1. Phosphate Anion Sensors
5. C-IDA BASED CATION SENSORS
6. C-IDA BASED SACCHARIDE SENSORS
CONCLUSION
ACKNOWLEDGEMENTS
REFERENCES
Fluorescence Indicator Displacement Assays (F-IDAs)
1. INTRODUCTION
2. F-IDA BASED ANION SENSORS
2.1. Phosphate Anion F-IDA Sensors
2.2. Sensors for Fluoride, Bicarbonate and Citrate Ions
3. SENSORS FOR SACCHARIDES
4. SENSORS FOR BIOMARKERS
5. SENSORS FOR PHARMACOLOGICAL DRUGS
6. SENSORS FOR NEUROTRANSMITTERS
7. SENSORS FOR EXPLOSIVES AND TOXIC SUBSTANCES
8. SENSORS FOR PEPTIDES AND METABOLIC WASTE PRODUCTS
CONCLUSION
ACKNOWLEDGEMENTS
REFERENCES
Metal Complexing Indicator Displacement Assays (M-IDAs)
1. INTRODUCTION
2. M-IDA BASED SENSORS FOR PHOSPHATE AND OTHER VITAL ANIONS
3. SENSORS FOR THE SACCHARIDES, WARFARE AGENTS AND BIOMARKERS
4. SENSORS FOR AMINO ACIDS, NEUROTRANSMITTERS, SULFIDES, AND T-DNA
CONCLUSION
ACKNOWLEDGEMENTS
REFERENCES
Recent Extensions of IDA-based Sensing Protocols
1. INTRODUCTION
2. ENANTIOSELECTIVE INDICATOR DISPLACEMENT ASSAYS (E-IDAS)
3. INDICATOR CATALYST DISPLACEMENT ASSAY (ICDA)
4. INTRAMOLECULAR INDICATOR DISPLACEMENT ASSAYS (I-IDAS)
5. REACTION BASED INDICATOR DISPLACEMENT ASSAYS (R-IDAS)
6. ALLOSTERIC INDICATOR DISPLACEMENT ASSAY (A-IDA)
7. MECHANICALLY CONTROLLED INDICATOR DISPLACEMENT ASSAYS (MC-IDAS)
8. DIMER DYE ASSEMBLY ASSAY (DDA)
9. QUENCHER DISPLACEMENT ASSAY (QDA)
10. CATALYTIC CHEMOSENSING ASSAY (CCA)
CONCLUSION AND OUTLOOK
ACKNOWLEDGEMENTS
REFERENCES
IDA-based Differential Sensory Arrays and Assays
1. INTRODUCTION
2. IDA OPERATED SINGLE ANALYTE SENSING VERSES DIFFERENTIAL SENSING
3. SENSORY ARRAY EXPERIMENTAL DATA ANALYSIS
4. DIFFERENTIAL SENSING OF ATP AND GLYCOSAMINOGLYCANS
5. DIFFERENTIAL SENSING OF PROTEINS, AMINO ACIDS AND GLYCOPROTEINS
6. DIFFERENTIAL SENSING OF ORGANOPHOSPHATES AND OTHER VITAL ANIONS
7. DIFFERENTIAL SENSING OF SACCHARIDES AND METABOLITES
8. DIFFERENTIAL SENSING OF POLYPHENOLS AND GINSENOSIDES
9. IDA-BASED MOLECULARLY IMPRINTED POLYMERIC SENSORY ARRAYS
CONCLUSION AND OUTLOOK
REFERENCES
Electrochemical Sensors Based on Indicator Displacement Assays
1. INTRODUCTION
2. TYPES OF ELECTROCHEMICAL SENSORS
2.1. Potentiometric Sensors
2.1.1. Ion-Selective Electrodes (ISEs)
2.1.2. Coated Wire Electrodes (CWEs)
2.1.3. Ion Selective Field Effect Transistors (ISFET)
2.2. Amperometric Sensors
2.3. Conductometric Sensors
3. TECHNIQUES USED IN ELECTROCHEMICAL SENSING
3.1. Voltammetry
3.1.1. Sweep Type Methods
3.1.2. Polarographic Techniques
3.2. Amperometry
3.3. Electrochemical Impedance Spectroscopy
4. IDA BASED ELECTROCHEMICAL SENSORS FOR SACCHARIDES
5. IDA-BASED ELECTROCHEMICAL SENSORS FOR BIOMARKERS
6. MISCELLANEOUS EXAMPLES
CONCLUSION
ACKNOWLEDGEMENTS
REFERENCES
LIST OF ABBREVIATIONS
LIST OF ABBREVIATIONS
Subject Index
Back Cover

Systemvoraussetzungen

Als PDF speichern Als Link merken