Protein Synthesis: Methods and Protocols

Name: Protein Synthesis: Methods and Protocols
Brand: Delve Publishing
Price: 207.99 EUR
Availability: OnlineOnly

Bhupendra Pushkar(Herausgeber*in)

Delve Publishing

Erschienen am 30. November 2020

282 Seiten

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978-1-77407-904-1 (ISBN)

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Inhalt

Cover
Title Page
Copyright
ABOUT THE EDITOR
TABLE OF CONTENTS
Glossary of Terms
List of Figures
List of Tables
List of Abbreviation
Preface
Chapter 1 Primary Structure and Three-Dimensional Arrangement of Proteins
1.1. Introduction
1.2. Primary Structure
1.3. Three-Dimensional Structure Of Proteins
1.4. Protein Secondary Structure
1.5. Tertiary Structure
1.6. Quaternary Structure And Symmetry
1.7. Conclusion
References
Chapter 2 History of Protein Synthesis (Cell-Free Protein Synthesis)
2.1. Introduction
2.2. The Archaeology Of Protein Synthesis - The 1940S: Forgotten Paradigms
2.3. Basic Mechanisms - The 1950s
2.4. Landmark Advances In The Development of Cell-Free Protein Synthesis Systems
2.5. Steps Toward An In Vitro Protein Synthesis System
2.6. The Golden Age of Translation - The 1960S
2.7. 1970S-1990S: A Brief Synopsis
2.8. Protein Synthesis And Translational Control: A Historical Perspective
2.9. Development of The Protein Synthesis Field
2.10. Origins of Translational Control
2.11. Conclusion
References
Chapter 3 t-RNA and Aminoacyl-tRNA Synthetases
3.1. Introduction
3.2. Structure Of tRNA
3.3. The Multiple Biological Functions Of tRNA
3.4. Structure And Classification Of Aarss
3.5. Aminoacyl- tRNA Synthetase Reactions
3.6. Structural And Biochemical Dissection Of Amino Acid Activation
3.7. Conclusion
Reference
Chapter 4 Polypeptide Chain Initiation, Elongation And Termination
4.1. Introduction
4.2. Polypeptide Chains
4.3. Preparing Polypeptide Chains
4.4. The Mechanism Of Protein Synthesis Or Translation
4.5. Conclusion
References
Chapter 5 Messenger RNA (MRNA) and Its Translation
5.1. Introduction
5.2. Messenger RNA (MRNA)
5.3. Prokaryotic MRNA Structure
5.4. Eukaryotic MRNA
5.5. Importance Of MRNA Translation
5.6. Translation
5.7. Translation: Beginning, Middle, And End
5.8. Initiation
5.9. Elongation
5.10. Termination
5.11. Conclusion
References
Chapter 6 Ribosome Structure and Function
6.1. Introduction
6.2. Parts Of The Ribosome
6.3. Size, Composition And General Structure
6.4. Conservation Of Structure
6.5. Techniques For Studying Ribosome Structure
6.6. Function Of A Ribosome
6.7. Ribosomes And Protein Synthesis
6.8. Conclusion
References
Chapter 7 Inhibitors Of Protein Synthesis, Antibiotics And Resistance
7.1. Introduction
7.2. Bacterial Protein Synthesis Inhibitors
7.3. Inhibitors Of Protein Synthesis
7.4. Antibiotics Target The Small Subunit of The Ribosome
7.5. Antibiotics Target The Large Subunit of The Ribosome
7.6. Antibiotic Resistance Mechanism
7.7. Conclusion
References
Chapter 8 Evolution of The Translation Apparatus
8.1. Introduction
8.2. Landmark Advances In The Development of Cell-Free Protein Synthesis Systems
8.3. Development of The Protein Synthesis Field
8.4. Insights To Ribosomal History From Trna Structure
8.5. Basic Theories of The Code Nature, Origin, And Evolution
8.6. The Origin Of tRNA
8.7. Sequence-Based Evolutionary Analysis of The Aarss
8.8. An "RNA-First" View of The Origin of Life
8.9. The First RNA Replicase
8.10. Conclusion
References
Index
Back Cover

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