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Editor-in-Chief:Daniel K. Podolsky, M.D. President, Professor of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.
Associate Editors:Michael Camilleri, M.D, Professor of Medicine and Physiology, College of Medicine, Mayo Clinic; Consultant in Gastroenterology, Mayo Clinic, Rochester.
J. Gregory Fitz, M.D, Dean, Southwestern Medical School, Distinguished Chair in Medical Science, UT Southwestern Medical Center, Dallas, TX, USA.
Anthony N. Kalloo, M.D, Professor of Gastroenterology and Director, Division of Gastroenterology and Hepatology, The Johns Hopkins Hospital, Baltimore, MD USA.
Fergus Shanahan, M.D, Professor and Chair, Department of Medicine and Director, Alimentary Pharmabiotic Centre, University College Cork, Cork University Hospital, Ireland.
Timothy C. Wang, M.D, Chief, Division of Digestive and Liver Diseases, Silberberg Professor Medicine, Department of Medicine and Irving Cancer Research Center, Columbia University Medical Center, New York, NY USA.
List of contributors ix
Preface xix
About the companion website xxi
PART 1 Anatomy and development
1 Esophagus: anatomy and structural anomalies 3Ikuo Hirano
2 Stomach and duodenum: anatomy and structural anomalies 13Eric Goldberg and Jean-Pierre Raufman
3 Small intestine: anatomy and structural anomalies 19Deborah C. Rubin and Jacob C. Langer
4 Colon: anatomy and structural anomalies 24Konstantin Umanskiy and Jeffrey B. Matthews
5 Pancreas: anatomy and structural anomalies 30David G. Heidt, Michael W. Mulholland, and Diane M. Simeone
6 Abdominal cavity: anatomy, structural anomalies, and hernias 36Kevin P. Murphy, Michael M. Maher, and Owen J. O'Connor
7 Gallbladder and biliary tract: anatomy and structural anomalies 43Theodore H. Welling
8 Liver: anatomy, microscopic structure, and cell types, 50Gary C. Kanel
PART 2 Gastrointestinal diseases
A Esophagus
9 Motility disorders of the esophagus 61Joan W. Chen, John E. Pandolfino, and Peter J. Kahrilas
10 Gastroesophageal reflux disease 72Kumar Krishnan, John E. Pandolfino, and Peter J. Kahrilas
11 Eosinophilic esophagitis 82Yael Haberman Ziv, Margaret H. Collins, and Marc E. Rothenberg
12 Esophageal infections and disorders associated with acquired immunodeficiency syndrome 85C. Mel Wilcox
13 Esophageal neoplasms 93Adam J. Bass and Anil K. Rustgi
14 Miscellaneous diseases of the esophagus: foreign bodies, physical injury, and systemic and dermatological diseases 102Seth D. Crockett, Evan S. Dellon, and Nicholas J. Shaheen
B Stomach
15 Disorders of gastric emptying 115Henry P. Parkman
16 Peptic ulcer disease 124Jonathan R. White, Krish Ragunath, and John C. Atherton
17 Zollinger-Ellison syndrome 135Robert T. Jensen
18 Gastritis and gastropathy 140David Y. Graham and Robert M. Genta
19 Tumors of the stomach 149Emad M. El-Omar and Chun-Ying Wu
20 Miscellaneous diseases of the stomach 153Tamas A. Gonda and Yanghee Woo
C Small intestine
21 Dysmotility of the small intestine and colon 157Michael Camilleri, Silvia Delgado-Aros, and Lawrence Szarka
22 Bacterial, viral, and toxic causes of diarrhea, gastroenteritis, and anorectal infections 170Gail A. Hecht, Jerrold R. Turner, and Phillip I. Tarr
23 Chronic infections of the small intestine 177George T. Fantry, Lori E. Fantry, Stephen P. James, and David H. Alpers
24 Disorders of epithelial transport, metabolism, and digestion in the small intestine 184Richard J. Grand
25 Short bowel syndrome 189Richard N. Fedorak, Leah M. Gramlich, and Lana Bistritz
26 Tumors of the small intestine 202Barbara H. Jung and Maria Rosario Ferreira
27 Miscellaneous diseases of the small intestine 208Marc S. Levin
D Inflammatory Bowel Disease
28 Ulcerative colitis: clinical manifestations and management 216William F. Stenson, William J. Tremaine, and Russell D. Cohen
29 Crohn's disease: clinical manifestations and management 225Gil Y. Melmed and Stephan R. Targan
E Colon
30 Polyps of the colon and rectum 234
Daniel C. Chung and John J. Garber III
31 Malignant tumors of the colon 238Jay Luther and Andrew T. Chan
32 Polyposis syndromes 246Randall W. Burt, Mary P. Bronner, and Kory W. Jasperson
33 Colorectal cancer screening 266Uri Ladabaum
34 Anorectal diseases 270Adil E. Bharucha and Arnold Wald
F Pancreas
35 Acute pancreatitis 287Hana Algül and Roland M. Schmid II
36 Chronic pancreatitis 307Joachim Mössner, Albrecht Hoffmeister, and Julia Mayerle
37 Hereditary diseases of the pancreas 317Carlos G. Micames and Jonathan A. Cohn
38 Cystic lesions of the pancreas 324James J. Farrell
39 Neuroendocrine tumors of the pancreas 329Peter J. Carolan and Daniel C. Chung
G Gallbladder and biliary tract
40 Gallstones 335Piero Portincasa and David Q.-H. Wang
41 Primary sclerosing cholangitis and other cholangiopathies 354Russell H. Wiesner and Kymberly D.S. Watt
42 Cystic diseases of the liver and biliary tract 361James L. Buxbaum and Shelly C. Lu
43 Tumors of the biliary tract 368Tushar Patel
H Liver
44 Acute viral hepatitis 374Marc G. Ghany and T. Jake Liang
45 Chronic hepatitis B viral infection 387Robert G. Gish
46 Hepatitis C virus infection 392Raymond T. Chung and Andrew Tai
47 Drug-induced liver disease 397Frank V. Schiødt and William M. Lee
48 Autoimmune hepatitis 405Richard Taubert and Michael P. Manns
49 Primary biliary cirrhosis 409Marlyn J. Mayo and Dwain L. Thiele
50 Hemochromatosis 415Paul C. Adams
51 Metabolic diseases of the liver 419Ronald J. Sokol and Mark A. Lovell
52 Alcoholic liver disease 423Jose Altamirano, Eric S. Orman, and Ramon Bataller,
53 Nonalcoholic fatty liver disease 428M. Shadab Siddiqui and Arun J. Sanyal
54 Hepatic fibrosis 436Don C. Rockey
55 Approach to the patient with ascites and its complications 447Guadalupe Garcia-Tsao
56 Liver transplantation 459Alyson N. Fox and Robert S. Brown, Jr.
57 Hepatocellular carcinoma 465Jorge A. Marrero and Amit Singal
58 Liver abscess 469Roman E. Perri and David S. Raiford
59 Vascular diseases of the liver 472Susana Seijo and Laurie D. DeLeve
I Miscellaneous
60 Intraabdominal abscesses and fistulae 477Peter Irving and Nyree Griffin
61 Diseases of the peritoneum, retroperitoneum, mesentery, and omentum 484Jennifer W. Harris, Scott D. Stevens, and B. Mark Evers
62 Obesity: treatment and complications 491Louis A. Chaptini and Steven Peikin
63 Bariatric surgery and complications 495Obos Ekhaese, Danny O. Jacobs, and Russell LaForte
64 Complications of AIDS and other immunodeficiency states, 501Phillip D. Smith, Nirag C. Jhala, C. Mel Wilcox, and Edward N. Janoff
65 Gastrointestinal manifestations of immunological disorders, 509Paula O'Leary and Fergus Shanahan
66 Parasitic diseases: protozoa, 515Ellen Li and Samuel L. Stanley Jr.
67 Helminthic infections of the gastrointestinal tract and liver, 524Thormika Keo, John Leung, and Joel V. Weinstock
68 Gastrointestinal manifestations of systemic diseases, 544Eran Israeli and Charles N. Bernstein
69 Skin lesions associated with gastrointestinal and liver diseases, 554Kim B. Yancey and Travis W. Vandergriff
70 Oral manifestation of gastrointestinal diseases, 574Vidyasagar Ramappa and Yashwant R. Mahida
71 Intestinal ischemia and vasculitides, 582Juan-Ramón Malagelada and Carolina Malagelada
72 Radiation injury in the gastrointestinal tract, 597Steven M. Cohn and Stephen J. Bickston
PART 3 Diagnostic and therapeutic modalities in gastroenterology
A Endoscopic
73 Upper gastrointestinal endoscopy 605Ebubekir S. Daglilar, Abdurrahman Kadayifci, and William R. Brugge
74 Capsule and small bowel endoscopy 621Jonathan A. Leighton and Shabana F. Pasha
75 Colonoscopy and flexible sigmoidoscopy 626Peter H. Rubin, Steven Naymagon, Christopher B. Williams, and Jerome D. Waye
76 Endoscopic retrograde cholangiopancreatography: diagnostic and therapeutic 634Mustafa A. Arain and Martin L. Freeman
77 Gastrointestinal dilation and stent placement 643Shayan Irani and Richard A. Kozarek
78 Management of upper gastrointestinal hemorrhage related to portal hypertensionTinsay A. Woreta and Zhiping Li
79 Endoscopic diagnosis and treatment of nonvariceal upper gastrointestinal hemorrhage 675David J. Bjorkman
80 Endoscopic therapy for polyps and tumors 680Mouen A. Khashab, Sergey V. Kantsevoy, and Heiko Pohl
81 Laparoscopy and laparotomy 698Ricardo Zorron and Gustavo Carvalho
82 Natural orifice translumenal endoscopic surgery (NOTES) 702Vivek Kumbhari and Anthony N. Kalloo
B Imaging
83 Plain and contrast radiology 722Marc S. Levine and Stephen E. Rubesin
84 Transabdominal sonography 732Stephanie F. Coquia, Linda C. Chu, and Ulrike M. Hamper
85 Endoscopic ultrasonography 741Marcia Irene Canto and Mouen A. Khashab
86 Computed tomography of the gastrointestinal tract 756Siva P. Raman, Karen M. Horton, Pamela T. Johnson, and Elliot K. Fishman
87 Magnetic resonance imaging 768Diane Bergin
88 Positron emission tomography in the gastrointestinal tract 782Manuela Matesan, Jonathan Sham, James Park, and Satoshi Minoshima
89 Radionuclide imaging of the gastrointestinal tract 804Harvey A. Ziessman
90 Abdominal angiography 820Kyung Jae Cho
91 Interventional radiology 842Todd R. Schlachter, Julius Chapiro, Rafael Duran, Vania Tacher, Camila Zamboni, Luke Higgins, and Jean-Francois Henri Geschwind
C Pathology
92 Liver biopsy and histopathological diagnosis 860Sugantha Govindarajan
93 Endoscopic mucosal biopsy: histopathological interpretation 878Elizabeth Montgomery and Anthony N. Kalloo
Index 931
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