This second edition volume provides a valuable source of information on the application of capillary electrophoresis (CE) and the many different aspects of clinical medicine. Chapters divided into seven parts focus on applications in clinical chemistry and small molecule analysis, applications in drug analysis, examples of CE applied to metabolomics, application in pediatrics, CE analysis on oncology, and CE analysis in virology. Written in the highly successful
Methods in Molecular Biology
series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge,
Clinical Applications of Capillary Electrophoresis: Methods and Protocols, Second Edition
aims to become a resource not only for clinical chemists, but also physicians and scientists who wish to apply these techniques to diagnosis and clinical research.
Reihe
Auflage
Sprache
Verlagsort
Verlagsgruppe
Illustrationen
51 farbige Abbildungen, 23 s/w Abbildungen
XII, 273 p. 74 illus., 51 illus. in color.
ISBN-13
978-1-4939-9213-3 (9781493992133)
DOI
10.1007/978-1-4939-9213-3
Schweitzer Klassifikation
An Overview of CE in Clinical Analysis.- Rapid and Sensitive Determination of Branched-Chain Amino Acids in Human Plasma by Capillary Electrophoresis with Contactless Conductivity Detection for Physiological Studies.- Monitorization of a1-Acid Glycoprotein Deglycosylation using SU-8 Microchips Electrophoresis with LIF Detection.- Glycoform Analysis of Alpha1-Acid Glycoprotein by Capillary Electrophoresis using Electrophoretic Injection.- On-Line Immunoaffinity Solid-Phase Extraction Capillary Electrophoresis-Mass Spectrometry for the Analysis of Serum Transthyretin.- Measurement of Neutral and Sialylated IgG N-glycome at Asn-297 by CE-LIF to Assess Hypogalactosylation in Rheumatoid Arthritis.- The Control of Glucose and Lactate Levels in Nutrient Medium after Cell Incubation and in Microdialysates of Human Adipose Tissue by Capillary Electrophoresis with Contactless Conductivity Detection.- Flow-Induced Dispersion Analysis (FIDA) for Protein Quantification and Characterization.- A Chiral Generic Strategy for Enantioseparation of Acidic and Basic Drugs using Short End Injection Capillary Electrophoresis: Application to Design of Experiment.- New Advances for Newborn Screening of Inborn Errors of Metabolism by Capillary Electrophoresis-Mass Spectrometry (CE-MS).- Capillary Electrophoresis-Mass Spectrometry for Metabolic Profiling of Biomass-Limited Sample.- Device Fabrication and Fluorescent Labeling of Preterm Birth Biomarkers for Microchip Electrophoresis.- Analysis of Inflammatory Mediators in New-Born Dried Blood Spot Samples by Chip-Based Immunoaffinity Capillary Electrophoresis.- Triplet-Repeat Primed PCR and Capillary Electrophoresis for Characterizing the Fragile X Mental Retardation 1 CGG Repeat Hyperexpansions.- A Capillary Electrophoresis UV Detection-Based Method for Global Genomic DNA Methylation Assessment in Human Whole Blood.- Capillary Electrophoresis Analysis of ProstateSpecific Antigen (PSA).- Prostate Protein N-Glycoylation Profiling by Means of DNA Sequencer-Assisted Fluorophore-Assisted Carbohydrate Electrophoresis.- Aptamer-Based Microchip Electrophoresis Assays for Amplification Detection of Carcinoembryonic Antigen.- Highly Sensitive SDS Capillary Gel Electrophoresis with Sample Stacking Requiring Only Nanograms of Adeno-Associated Virus Capsid Proteins.
