Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between 'canonical' and 'non-canonical' forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of 'non-canonical' autophagy. The book discusses all forms of 'non-canonical' autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying 'non-canonical' autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies.
- Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy
- Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes
- Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-12-820911-0 (9780128209110)
Schweitzer Klassifikation
1. Introduction: canonical vs non-canonical autophagy2. Overview of Canonical Autophagy 3. Overview of Non-Canonical Autophagy4. LC3-associated phagocytosis (LAP)5. Autophagy-dependent cell death (ADCD) 6. Therapeutic targeting of non-conventional autophagy: potential benefits and pitfalls