Radioimmunoassay in Basic and Clinical Pharmacology

1 Radioimmunoassay: Historical Aspects and General Considerations.- 2 Basic Principles of Antigen-Antibody Interaction.- 3 Production of Antisera by Conventional Techniques.- 4 Production of Monoclonal Antibodies for Radioimmunoassays.- 5 Radioiodination and Other Labeling Techniques.- 6 Strategies for Developing Specific and Sensitive Hapten Radioimmunoassays.- 7 How to Improve the Sensitivity of a Radioimmunoassay.- 8 Statistical Aspects of Radioimmunoassay.- 9 Validation Criteria for Radioimmunoassay.- 10 Measurement of Opioid Peptides in Biologic Fluids by Radioimmunoassay.- 11 Radioimmunoassay of Pituitary and Hypothalamic Hormones.- 12 Radioimmunoassay of Nonpituitary Peptide Hormones.- 13 Radioimmunoassay of Gastrointestinal Polypeptides.- 14 Radioimmunoassay of Atrial Peptide Blood and Tissue Levels.- 15 Immunochemical Methods for Adrenal and Gonadal Steroids.- 16 Radioimmunoassay of Thyroid Hormones.- 17 Radioimmunoassay of Catecholamines.- 18 Radioimmunoassay of Prostaglandins and Other Cyclooxygenase Products of Arachidonate Metabolism.- 19 Radioimmunoassay of Leukotrienes and Other Lipoxygenase Products of Arachidonate.- 20 Radioimmunoassay of Cyclic Nucleotides.- 21 Radioimmunoassay of Platelet Proteins.- 22 A Competitive Binding Assay for Heparin, Heparan Sulphates and Other Sulphated Polymers.- 23 Radioimmunoassay of the Somatomedins/lnsulin-like Growth Factors.- 24 Radioimmunoassay of Drugs and Neurotransmitters.