Introduction to Adaptive Trial Designs and Master Protocols

Rezensionen / Stimmen

'A delightful, easy-to-read and must-have primer for anyone offering a course on basic concepts, ingredients, attributes, and different types of, including common misconceptions and practical considerations for, adaptive clinical trials and master protocols.' Lehana Thabane, Professor, Department of Health Research Methods, Evidence, and Impact, McMaster University, Canada 'This book fulfils an important need, providing a broad overview of recent work in innovative approaches to clinical trials. It covers two major types of innovative trial design that are becoming more widespread in clinical research: adaptive designs and master protocols. For readers who wish to delve into more depth, it provides a thorough review of literature on the topic. It also showcases available software, both commercial and free, and provides many real case studies of where the designs have been used in real trials. The book is written by three experts in the field who understand well the benefits and limitations of these approaches. It is relevant to those who work in academic trials as well as the pharmaceutical industry. I would highly recommend it as a great resource for clinical trialists who want to understand these approaches better.' James Wason, Professor of Biostatistics, Newcastle University