Aging: From Fundamental Biology to Societal Impact examines the interconnection of the cellular and molecular basis of aging and societal-based challenges and innovative interventions. Sections take a societal-based angle on aging, describing several flagship initiatives for healthy living and active aging in different regions, cover the biology of aging which includes the hallmarks of aging, explain the pathophysiology of aging, describing different comorbidities associated with aging and possible interventions to decrease the impact of aging, and envision future and innovative measures to tackle aging-related morbidities.Contributions from an interdisciplinary panel of experts cover such topics as the biology of aging to physical activity, nutrition, psychology, pharmacology, health care, social care and urban planning.
- Provides a cross-disciplinary approach to aging at both the biological and societal level
- Highlights frontline scientific knowledge in the biology of aging and its translation into societal interventions
- Offers insights on the value of aging research and its future impact from a fundamental and translation point-of-view
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Illustrationen
Approx. 100 illustrations (20 in full color)
Dateigröße
ISBN-13
978-0-12-824131-8 (9780128241318)
Schweitzer Klassifikation
Section 1. The Societal Burden of Aging1. Aging at a global level2. The financial and economical burden of aging worldwide3. Flagship initiatives for healthy living and active aging in Europe4. Flagship initiatives for healthy living and active aging in Africa5. Flagship initiatives for healthy living and active aging in North America6. Flagship initiatives for healthy living and active aging in Asia and Oceania7. Flagship initiatives for healthy living and active aging in Central and South AmericaSection 2. The Biology of Aging8. A metabolic and mitochondrial angle on aging9. Intracellular communication and aging10. Genomic instability and telomere attrition11. Cellular senescence during aging12. The epigenetics of aging13. Disrupted cellular quality control mechanisms in aging14. Deregulated nutrient sensing in aging15. Stem cells fitness and aging16. Programming of early agingSection 3. Aging-related physiology, disease and prevention of aging-related diseases17. Adherence to therapy and polymedication18. Frailty and cognitive decline19. Cardiovascular aging20. Aging-related neoplasia21. Inflammation22. Geroscience: An unifying view on aging as a risk factor23. Building healthy agingSection 4: The Future and Innovation in Aging24. The future of innovation in aging25. Machine learning in the context of better healthcare in aging26. The knowledge and research in aging for the future27. The future of integrated care in aged individuals28. Moving from reactive to preventive medicine29. Personalized medicine: will this work for decreasing aging-related morbidities30. Anti-aging interventions: myths and realities
