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This book subtly presents the Peste des Petits Ruminants Virus (PPRV), a morbillivirus closely related to rinderpest virus, that decimates sheep and goats along with those of other susceptible domestic ruminants and many wildlife species. Following its first introduction to the West Africa in 1940, PPRV was rapidly disseminated across sub-Saharan Africa, the Middle East and Southern Asia. Recent outbreaks of PPR in Morocco and European part of Turkey are posing continuous threats to many European countries.
This book focuses on the key dynamics of this deadly disease, and incorporates considerable historical detail, infection biology, comparative molecular biology, and pathophysiology of the disease. The accurate disease diagnosis, management, and prevention of the disease are crucial for clinicians. Thus, three chapters emphasize the traditional prophylactic measures, clinical outcome of the disease and clinical disease assessments. The genomic organization and molecularbiology of PPRV is described comprehensively. Because of the current sensitivity about an emergence of PPRV and successful Global Rinderpest Eradication Programme, finally a chapter is dedicated to explore the possibilities to control and eradicate the PPRV from the globe, the way similar to rinderpest virus. Collectively, this book consists of high quality scientific and historical research contributed by the top experts in the field, from all around the globe. Moreover, editor's vast experience with PPRV and collaborations with other researchers worldwide make this book unique.
This book offers a valuable reference source for virologists, field veterinarians, infection and molecular biologists, immunologists, scientists in related fields and veterinary school libraries.
Prof. Muhammad Munir is a virologist at the Lancaster University and has over 15 years of experience on viruses of animal, human and zoonotic (viruses which leap from animal to human) importance. Prof Munir has written and edited two books on PPRV and several books on other viruses and is author of over 25 chapters in different books and has published over 170 research articles in the field of virology. Prof Munir is leading virologist and has been speaking to global media for over 1000 times including BBC, CNN, SkyNews, Al-Jazeera, France 24, iTV, DW, CGTN, amongst others to discussed different emerging viral diseases, around the globe.
Dr. Muhammad Abubakar is a veterinary epidemiologist and has over 20 years experience in different areas of animal health. Dr Abubakar has written and edited books on various aspects of animal health and has published over 100 research and review articles in the field of epidemiology and microbiology. Dr Abubakar is also leading One health expert and has participated in the development of national action plans relating to AMR and zoonosis. He has been associated with the FAO of the United Nations for activities relating to national animal disease control programs.
Chapter 1: Challenges and Opportunities in the Eradication Campaign of PPR.- Chapter 2: Socio-economic dynamics of PPR in developing countries.- Chapter 3: Strategic Control of Peste des Petits Ruminants.- Chapter 4: PPR eradication in Africa Perspective.- Chapter 5: Host Spectrum of PPRV.- Chapter 6: PPR infection crossing between domestic and wild hoofed mammals - does this matter for virus eradication?.- Chapter 7: Molecular Virology of PPRV.- Chapter 8: Pathogenesis of Peste des Petits Ruminants Virus.- Chapter 9: Concurrent and PPRV Infection in Small Ruminants.- Chapter 10: Current advances in molecular genomic-based detection and sequencing of peste des petits ruminants virus.- Chapter 11: Advanced Serological Diagnosis of PPRV.- Chapter 12: Advances in vaccination against PPRV.
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