Reproductive Immunology: Basic Concepts gives a holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. This interaction is critical for the support of the human fetal semiallograft and the protection against infections. The book covers various topics such as B cells, macrophages, T cells, discussion on fetal signals and their impact on maternal reproductive cells such as endometrial cells, mast cells, and the role of fetal Hofbauer cells, the immune regulatory role of glucorticoids, and many other novel topics within the field of reproductive immunology.
Edited and written by experts in the field, this book introduces the up-to-date knowledge of the role of the immune system during pregnancy and provides the necessary background to understand pregnancy complications associated with alterations in the functioning of the immune system. The book provides a complete discussion on the immunological aspects of pregnancy and serves as a great tool for research scientists, students, reproductive immunologists and OBGYNs.
- Shows the detailed evaluation of the knowledge related to each immune cell type in the pregnant and not pregnant uterus
- Evaluates each immune cell type and its function during specific reproductive events
- Provides the biological background for understanding the clinical aspects that will be discussed in subsequent volumes in the series
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-12-818930-6 (9780128189306)
Schweitzer Klassifikation
1. The role of the immune system during pregnancy: General concepts2. Presentation and recognition of placental, fetal, and pathogen-derived antigens in human pregnancy3. Uterine macrophages: Essential roles for a successful human pregnancy4. Natural killer cells in reproduction: Before, during and after pregnancy5. To B (e) born: New concepts concerning B cells throughout pregnancy6. Neutrophils: Diverse functions in the endometrium of cycling women and during pregnancy7. Regulatory T cells: Master regulators for the success of pregnancy8. Immunology of the decidua9. Mechanism of glucocorticoid action in immunology-Basic concepts10. Endocrine control of mucosal immunity in the human female reproductive tract: Bridging implantation with pathogen protection11. The nature of the immune response in microbial-associated and sterile intraamniotic inflammation12. Autoimmunity, regulatory T cells, and pregnancy: Maintaining the balance13. Mucosal immunology of the female reproductive tract and its regulation by female sex hormones14. Toll-like receptors and NOD-like receptors at the implantation site15. Hofbauer cells and placental viral infection16. Gamma/delta T cells in pregnancy17. Placental regulation of immune functions18. TAM receptors in pregnancy19. The epigenetic regulation of the immune system during pregnancy20. Interactions between the epithelial barrier and the microbiota in the reproductive tract