Bioconjugation

Site-Specific Conjugation of Thiol-Reactive Cytotoxic Agents to Non-Native Cysteines of Engineered Monoclonal Antibodies.- Application of Next Generation Maleimides (NGMs) to Site-Selective Antibody Conjugation.- Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent.- Engineering Dual-Variable-Domains for the Generation of Site-Specific Antibody-Drug Conjugates.- Efficient Production of Homogeneous Lysine-Based Antibody Conjugates Using Microbial Transglutaminase.- Engineering Antibodies with C-Terminal Sortase-Mediated Modification for Targeted Nanomedicine.- CRISPR/Cas9-Mediated Genetic Engineering of Hybridomas for Creation of Antibodies that Allow Site-Specific Conjugation.- Site-Specific Modification of Proteins via Trypsiligase.- Site-Selective Functionalization of Nanobodies Using Intein-Mediated Protein Ligation for Innovative Bioconjugation.- Site-Specific Bioconjugation Using SMARTag ^â Technology: A Practical and Effective Chemoenzymatic Approach to Generate Antibody-Drug Conjugates.- Protein Labeling and Bioconjugation Using N-Myristoyltransferase.- One-Step Fluorescent Protein Labeling by Tubulin Tyrosine Ligase.- Enzymatically Catalyzed Radiofluorination of Biomolecules.- Site-Selective Enzymatic Labeling of Designed Ankyrin Repeat Proteins Using Protein Farnesyltransferase.- Homogeneous Antibody-Drug Conjugates via Glyco-Engineering.- Labeling Proteins at Site-Specifically Incorporated 5-Hydroxytryptophan Residues Using a Chemoselective Rapid Azo-Coupling Reaction.- Facile Site-Specific Multi-Conjugation Strategies in Recombinant Proteins Produced in Bacteria.- Site-Specific Photocrosslinking to Immunoglobulin G Using Photoreactive Antibody-Binding Domains.- SpyTag-SpyCatcher Chemistry for Protein Bioconjugation In Vitro and Protein Topology Engineering In Vivo.- FN3 Protein Conjugates for Cancer Diagnosis and Imaging Studies.