Lymphocyte Activation and Differentiation

Name: Lymphocyte Activation and Differentiation | Fundamental and Clinical Aspects. Proceedings of the 18th International Leucocyte Culture Conference. La Grande Motte, France, June 19-24, 1987
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Fundamental and Clinical Aspects. Proceedings of the 18th International Leucocyte Culture Conference. La Grande Motte, France, June 19-24, 1987

J. C. Mani J. Dornand(Herausgeber*in)

De Gruyter (Verlag)

1. Auflage

Erschienen am 8. Juli 2019

XXI, 960 Seiten

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Intro
PREFACE
CONTENTS
INTRODUCTION
Fundamental and Clinical Aspects of Lymphocyte Activation and Differentiation
PLENARY LECTURE
Oncogenes and Multistep Carcinogenesis
SYMPOSIA BIOCHEMICAL AND CELLULAR ASPECTS OF LYMPHOCYTE ACTIVATION
Biochemical and Molecular Events Controlled by Lymphoid and Myeloid Growth Factors
PGE2 Inhibition of Human T Lymphocytes Proliferation: Regulatory Effect of PGE2 on the Intra-Cellular Signaling Pathways
Structure-Function Relationships for the Interleukin 2 Receptor
Monovalent Cation Fluxes as Regulators of Critical Nuclear Events in Lymphocyte Activation: Mirror Image Processes in Differentiation and Proliferation
Diacylglycerol, Calcium, cAMP and cGMP Mediate Qualitatively Distinct Protein Kinase C Translocation Events in Normal B Lymphocytes
Phosphorylation of Prosolin and Leucocyte Growth Regulation
DIFFERENTIATION OF T AND B LYMPHOCYTES
Regulation of Human B Cell Function
The Role of Lymphokines in the Immunoglobulin Class Switch
Mouse and Human B Cell Activating Factors
Molecular Cloning of the Murine T11 (CD2) cDNA
Antigen Expression and Proliferative Activity during B and T Cell Development
MOLECULAR BIOLOGY OF LEUCOCYTES (ANTIGENS, RECEPTORS, INTERLEUKINS)
The Molecular Biology of the Multisubunit Interleukin-2 Receptor
Expression and Rearrangement of T Cell Receptor Genes in Human Leukemic T Cell Lines
The Human T-Cell Rearranging ? Genes (TRG?)
Immunoglobulin Gene Expression
Structure and Expression of Mouse Fcy Receptor II (FcyRII)
VIRUS-INDUCED LYMPHOCYTE DYSFUNCTIONS
The Impact of the Presence of EBV on the Interaction of B Cell Lines with T Lymphocytes
Induction of B Cell Activation Markers by Epstein-Barr Virus
Production of Interleukin-1 (IL1) by EBV-Infected Cells
DNA-Mediated Gene Transfer of Epstein-Barr Virus Receptor onto Murine Fibroblasts
ACCESSORY CELL FUNCTIONS
Modulation of IL1 Receptor Expression by IL1, Prostaglandins and Glucocorticoids
Tumor Necrosis Factors: Modulation of Synthesis and Biological Activities
Analysis of the Structure and Function of Immunectin
Natural Effector Cells of the Intestinal Epithelium: Ontogeny, Function, and Regulation
Analysis of Ia-Transfected Fibroblasts: Antibody and T Cell Recognition Sites Segregate with the 31 Domain of the E3 Polypeptide Chain
WORKSHOPS WORKSHOP A. GROWTH AND DIFFERENTIATION FACTORS
Inhibition by Cyclosporin A of the IL2 Dependent Autocrine Growth in a Human Tumor T Cell Line and Fate of IL2 Receptors after Endocytosis
Interleukin B, a B Cell-Derived Lymphokine
Induction and Enhancement of Lymphokine Gene Expression in Human T Cell Clones Transfected with HTLV-I pX cDNA
Evidence for a Human B Cell Activating Factor Acting on Resting B Lymphocytes
Splicing Intermediates of the IL-2 Receptor (p55 Subunit)
The Role of Plasminogen Activator in Regulating T Cell Proliferation and Interferon Production
Membrane and Soluble IL2-R Produced by Human T Cell Clones: A Comparative Study
Phenotype and Cytokines Production by Human Myeloma Cell Lines
B + Null Cell-Derived Prothymocyte Differentiating Activity (PTDA): Biological Properties and Physicochemical Characterization
TDM-Activated Macrophages Produce a Cytostatic Factor Distinct from TNFa, IFNa,ß, and IL-1
Characterization of a Factor Produced by Human Alloreactive T Cell Clones
WORKSHOP B. MECHANISMS OF AUTOIMMUNITY
Effector Mechanisms of Autoimmune Diseases
T Cell Response to Myelin Basic Protein in Healthy Subjects and Multiple Sclerosis Patients
Active T Cell Regulation of Autoimmune Responses in Autoimmune and "Nonautoimmune" Spleen Cell Populations
Interleukin-2 Receptor Targeted Immunotherapy of Autoimmune Diseases: Treatment Strategies for Type I Diabetes
Protection of Non-Obese Diabetic (NOD) Mice from Insulitis by Neonatal Injection of F⊂&1&/sub& Spleen Cells
WORKSHOP C. ONCOGENES AND LEUCOCYTE TRANSFORMATION
Complex Transcriptional Regulation of Nuclear Proto Oncogenes: Existence of a Block to Elongation in C-Myc and C-Fos Genes
Determinants of C-Fos and C-Myc mRNAs Instability
Cloning and Functional Analysis of the Human C-fms Gene
Effects of Proliferative (Interleukin, Colony Stimulating Factors) and Antiproliferative (Cyclic AMP, Interferon) Signals on Gene Expression in Myeloid and Lymphoid Cell Lines
The Progession to Tumourigenes is Following Transformation of Murine Myelomonocytic Cell by V-Myc
HTLV-I Infection of a Human Antigen Specific Proliferating/Cytotoxic T Cell Clone Results in a Loss of Cytotoxicity but does not Affect the T Cell Receptor
WORKSHOP D. EXPERIMENTAL MODELS OF IMMUNOMODULATION
Roles of Monokines in the Nonspecific Host Defence Stimulated by Exogenous Agents
Enhancement of the Immune Response Using a Synthetic B-Lymphocyte Mitogen Covalently Linked to Antigens
Effects of in vivo Treatment of Mice with Anti-Murine T3 Antibody: Suppression of Transplantation Responses
Gamma-Interferon Protects Listeria-Susceptible BALB/c Mice from Lethal Listeriosis without Affecting the Development of Protective Immunity
Effect of a Lipophilic Muramylitri peptide on Gamma-Interferon Induced Major Histocompatibility Antigen (MHC) and Leu-M3 Antigen Changes in Human Monocytes
Effect of Cyclosporin A (CsA) on the Induction of Memory T Lymphocytes
Modulation by Cyclosporin A (CsA) of the Immune System of Mice Infected with Lymphocytic Choriomeningitis Virus (LCMV)
Modulation of Lymphocyte Activation in vitro by a Soluble Placental Factor
The Role of Interleukins and the Interleukin-2 Receptor in the Pathogenesis of Murine Cutaneous Leishmaniasis
In vitro Studies of Synthetic Glycolipids: A New Class of Compounds with Immunomodulating Activity
Immunotoxicity Studies of PCB (Aroclor 1254) in the Adult Rhesus (Macaca mulatta) Monkey
Human Cytomegalovirus Induces Alterations in Mixed Lymphocyte Reactions
WORKSHOP E. IMMUNODEFICIENCIES
Immunological Aspects of AIDS and HIV Infection
Studies Regarding the Interaction of the T4 (CD4) Molecule with the Envelope Protein gp120 of the Human Immunodeficiency Virus (HIV)
Low Level Re-Expression of the Silent MHC Class-II Genes in the Lymphoblasts from Patients with the HLA-Class II Deficient SCID
Adenylate Cyclase and 5'Nucleotidase Activities of Peripheral Blood Mononuclear Cells is Psoriasis
WORKSHOP F. NATURAL KILLER CELLS
Natural Killer Cells
Characterization and Population Kinetics of Liver-Associàted Large Granular Lymphocytes (Natural Killer Cells)
Modulation of Lymphonkine Activated Killer Activity of Lymphocytes Isolated from Human Peripheral Blood and Bone Marrow by Recombinant IL4
Inhibition of Human Natural Killer Cells by Resistant Target Cells
Changes in Gene Expression Associated with Activation or Inhibition of Natural Killer Function
Fibronectin Expression by Endogenous and Activated NK Cells
Cytolytic Potential of CD3⊃&+&/sup&4⊃&-&/sup&8⊃&-&/sup& T Cells with Differently Organized T Cell Receptor Y Chains
WORKSHOP G, DIFFERENTIATION AND ACTIVATION OF T LYMPHOCYTES
CD1a Molecules Form Intermolecular Complexes with HLA Class I Molecules or Other CD1 Molecules on Normal Human Thymus Cells
The CD2 Pathway of Activation. Epitope Requirements, Linkage to Other Surface Molecules and Early Biochemical Events
A T-Cell Surface Molecule Different from CD2 is Involved in Spontaneous Rosette Formation with Erythrocytes
A Dual Function of the T4 Molecule in the Cytolytic Activity of Human T Cell Clones
Role of Antigen-Specific T Cell Receptor and Associated Proteins in the Activation of a Cytolytic T Cell Clone Analysed by Protein Phosphorylation and by T Cell Receptor Negative Variants
Y-Chain T Cell Receptors on Denoritic Epidermal Cells
Stimulation of T Cells via LY-6C: A Phssphatidylinositol-Anchored Cell Surface Molecule which Generates Intracellular Calcium Mobilization upon Cross-Linking
New Subgroups in the Human T Cell Rearranging VG Gene Locus
Genomic Organisation of the Constant Regions of the Human T-Cell Rearranging Gene G
Second Signals for T Cell Mitogenesis Provided by a MAbs CD45 (T200) and CD5 (T1)
WORKSHOP H. DIFFERENTIATION AND ACTIVATION OF B LYMPHOCYTES
Immunobiology of B Lymphocytes
Regulation of B Lymphocyte Responsiveness by Multiple Cytokines
Influence of IL4 on the Induction of Immunoglobulin Secretion by BCAF-Containing Supernatant
Early B Cells Immortalized by Epstein-Barr Virus (EBV) - A Phenotypic Study
The Human B Cell Repertoire: Multispecificity as a Major Characteristic of Antibodies Secreted by Human EBV-Transformable Cord Blood B Cells
Analysis of Excessive B Cell Growth in Lymph Nodes of L. major Infected Mice: The Effect of L. major Specific T-Cell Clones
Antibody Response in vitro of Human Peripheral Blood Lymphocytes: Application of a Limiting Dilution Method
Frequency Analysis of Functional Immunoglobulin C⊂&E&/sub& Gene Expression in LPS-Reactive Murine B Cells
Changes in Gene Expression in Differentiating B Lymphocytes
Regulation of Lipopolysaccharide (LPS)-Induced B Cell Differentiation by Ly-5 and Uyb-2 Molecules
WORKSHOP I. LIPIDIC MEDIATORS OF THE IMMUNE RESPONSE
Phospholipid-Derived Mediators and the Immune Response
Anti-Oxidants and IL2 Synthesis
Role of Lipoxygenase Pathway Products in IL2 Synthesis
Platelet Activating Factor (PAF) Induces Human Suppressor Cell Activity
PAF-Acether Induces an Enhanced Release of Interleukin-1 (IL-1) from Human Monocytes
Down-Regulation of CD2 and CD3 Antigen Expression by PAF-Acether
WORKSHOP J. NEURAL MODULATION OF IMMUNITY
Neuroendocrine Modulation of Immunity
Cyclic AMP Response to Dopamine in the Human Monocyte-Like Cell Line U-937
ß-Endorphin Inhibits Thy-1 Antigen Expression on Murine Thymocytes and Antagonizes Thymosin Fraction V Action
WORKSHOP K. BIOCHEMISTRY OF LEUCOCYTE STIMULATION AND EFFECTOR MECHANISMS
Genes Preferentially Expressed in Cytolytic T Cells
Signal Transduction in Lymphocyte Activation
IL-2 Mediated Induction of Lytic Granules, Perforin, and BLT-Esterase in Potent, Granule-Free Cytolytic T Lymphocytes Indicates an Alternative Function of Lytic Granules
Extracel1ular ATP Initiates the Proliferative Response of PMA-Activated Medullary Thymocytes by Increasing their Cytosolic Free Calcium Concentration
Evidence for a Kinase Cascade Stimulated by Interleukin 2 in Cytotoxic T Cell Clones
The Regulation of Cytoskeletal Protein Gene Expression in Lymphocytes
Protein Phosphorylation During T Cell Activation
Clues to Mechanisms of Activation for Killing from the Observations of Changes in Intracellular (Ca⊃&++&/sup&) in Individual Cytolytic T Cells and Targets
Induction of Activation Signals in Human T Lymphocytes
Both Lyt2⊃&+&/sup& and L3T4⊃&+&/sup& Cell Subsets Secrete the Serine Esterase Granzyme A in Response to a Specific Antigenic Stimulus
WORKSHOP L. ACCESSORY CELLS-LYMPHOCYTE INTERACTIONS
Accessory Cells-Lymphocyte Interactions
A Role for HLA-Class I Molecules from Accessory Cells in T-Cell Activation
Adhesion Molecules of Monocytes
Cellular and Molecular Basis of Self-Induced Proliferation of T Lymphocytes (SIPofT)
Human T Cell Activation: Participation of T Cell Differentiation Antigen Cluster 2 (CD2) in the Generation and/or Transduction of Accessory Cell Signals
WORKSHOP PI. IDIOTYPIC REGULATION
The Influence of Vk Gene Polymorphism on the Induction of Silent Idiotypes in the Arsonate System
Allogeneic Manipulation of the "GAT" Idiotypic Cascade does not Influence the VH Gene Usage
Specific Suppression of the Primary Antibody Response with Immune Complexes Formed in Antibody Excess Depends on the Idiotype and the Isotype of the Antibody Forming the Complex
The HLA-Restricted Presentation of Idiotype to Human Anti-Idiotypic T Cell Clones does not Require Processing by Antigen Presenting Cells
Idiotypic Predominance Alteration in Anti-Arsonate Response by Priming with Anti-Idiotypic Antibodies
Anti-Idiotype Induction of Humoral Immunity in Cattle
Anti MHC-Receptor Cytotoxic T Lymphocytes: Their Role in the Specific Resistance to Graft-Versus-Host Reaction
Altered Anti-Idiotype Response to a(1-3)Dextran-Associated Idiotypes in Mice Bearing an X-Linked Immune Defect
WORKSHOP N. COMPLEMENT RECEPTORS
Human CD3 Complement Receptors
Influence of Antigen-Bound Complement Components C3b and C4b in Activation of Human T-Cell Clones
Human C3 and C3dg Stimulate Proliferation of a Pre-B Lymphoblastoid Cell Line via CR2 Complement Receptor
Activation of B Lymphocytes by Zymosan-Bound C3 Fragments
Contribution of C3 Fragments to Lymphocyte Mediated Lysis of CR2 Carrying Cells
In vivo" and "in vitro" Modulation of CR1 (C3b Receptor) Expression by its Ligand C3b
WORKSHOP O. MAJOR HISTOCOMPATIBILITY COMPLEX
MHC in Leucocyte Biology
HLA Class I a1, a2, and ß2-Microglobulin Domain Interactions
Diversity and Function of Human Class II MHC Antigens
DRa-DQß Mismatched Isotype Pairing Occurs in EBV Transformed B Cell Lines
Distinct Epitopes for K⊃&d&/sup&-Restricted Cytolytic T Cells Specific for HLA-CW3 or HLA-A24 Map to the same Region of HLA
Resistance or Susceptibility of Human Target Cells to NK Lysis: Correlation with the Surface Expression of HLA Class I Molecules and Induction of Susceptibility by Monoclonal Anti Class I Antibodies
WORKSHOP P (SANOFI). CLINICAL APPLICATIONS OF ANTILEUCOCYTE MONOCLONAL ANTIBODIES
Anti-Leucocyte Monoclonal Antibodies: From Laboratory Reagents to Therapeutic Agents
Treatment of Donor Bone Marrow with FabT101 Ricin A-Chain Immunotoxin for the Prevention of Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation
Monoclonal Antibodies for Bone Marrow Purging before Transplantation: A Brief Review
Comparative Efficiency of an Immunomagnetic Purging Procedure and a Rabbit Complement Lysis to Eliminate BL Cells from the Bone Marrow
In vivo Antigenic Modulation of CD5⊃&+&/sup& Cells in Renal Transplanted Patients Receiving Anti-CD5 Antibody Infusions
In vivo Therapy by CD8 Monoclonal Antibody for Delays to Hematological Recovery after Autologous Bone Marrow Transplantation
Autologous Bone Marrow Transplantation for Acute Lymphoblastic Leukemia in Remission. In vitro Purging of Inoculum with Monoclonal Antibodies and Complement
Immunosuppression by Murine Monoclonal Antibodies: The Rhesus Monkey Used for Preclinical Testing
Therapeutic Applications of Monoclonal Antibodies for Lymphoma and Leukemia
BMA 031 - The TCR Specific Monoclonal Antibody for Clinical Applications
Immunoassays for the Monitoring of Kidney Graft's Transplanted Patients under 33B3.1 MOAB Therapy
Prospective Randomized Studies of T Cell Depletion in HLA Matched Bone Marrow Transplantation (BMT) for Leukemia: 2 Studies of the GEGMO in 92 Patients
A Monoclonal Anti Interleukin 2 Receptor Prevents Human Kidney Graft Rejection
Clinical Pharmacology of 0KT3
Introduction to the Clinical Use of Monoclonal Antibodies as Immunosuppressive Agents
General Considerations on the Quality Control of Monoclonal Antibodies before Therapeutic Use in Man
Immunotoxins with Therapeutic Use in Man
AUTHOR INDEX
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