Cambridge Textbook of Neuroscience for Psychiatrists

I. Cells: 1.1. Neurons; 1.2. The physiology of neurons, synapses and receptors; 1.3. Modelling single neurons and their combinations in circuits; 1.4. Glia; II. Neurotransmitters and Receptors: 2.1. The chemical synapse; 2.2. Classification of receptors: metabotropic and ionotropic receptors; 2.3. Neuronal receptors and drug targets; 2.4. Basic pharmacology of specific neurotransmitter pathways; 2.5. Neuropeptides; 2.6. Genetic association studies and neurotransmitter pathways; 2.7. Opioids and common recreational drugs; III. Basic Techniques in Neuroscience: 3.1. Recording from the brain; 3.2. Perturbing brain function; 3.3. Animal models of psychiatric disease; 3.4. Data analysis and computational modelling; 3.5. Functional neuroimaging and connectivity; IV. Neuroanatomy: 4.1. Fundamentals; 4.2. The basal ganglia; 4.3. The temporal lobes; 4.4. The frontal lobes; 4.5. White matter pathways; 4.6. Ascending neurotransmitter systems; V. Neural Circuits: 5.1. Appetite; 5.2. Sleep; 5.3. Sex and sex hormones; 5.4. Violence and aggression; 5.5. Nociception and pain; 5.6. The motor system and movement disorders; 5.7. Computational models of learning; 5.8. Habit formation; 5.9. Reward, pleasure and motivation; 5.10. Emotion; 5.11. Perception; 5.12. Attention; 5.13. Apathy, anhedonia and fatigue; 5.14. Memory; 5.15. Fronto-executive functions; 5.16. Empathy and theory of mind; 5.17. Language; 5.18. Brain networks and dysconnectivity; VI. Modulators: 6.1. The hypothalamic-pituitary (Neuroendocrine) axis; 6.2. The stress response and glucocorticoids; 6.3. Adrenal steroids; 6.4. Inflammation and immune responses; VII. Genetics: 7.1. Basic genetic principles and the history of gene identification; 7.2. Common variation; 7.3. Rare variation; 7.4. Epigenetics; 7.5. The clinical application of genetics in psychiatry; VIII. Neurodevelopment and Neuroplasticity: 8.1. The development of brain structure and function; 8.2. Neurodevelopmental models of psychiatric disorders; 8.3. Attachment; 8.4. Neuroplasticity; 8.5. Intelligence and intellectual disability; IX. Integrated Neurobiology of Specific Syndromes and Treatments: 9.1. Autism; 9.2. Attention deficit hyperactivity disorder; 9.3. Drug use, addiction, tolerance, withdrawal and relapse; 9.4. Anxiety disorders; 9.5. Post-traumatic stress disorder; 9.6. Obsessive-compulsive and related disorders; 9.7. Major depressive disorder; 9.8. Bipolar affective disorder; 9.9. Psychosis; 9.10. Schizophrenia; 9.11. Borderline personality disorder; 9.12. Self-harm and suicidality; 9.13. Medically unexplained symptoms; 9.14. Delirium; 9.15. Perinatal disorders; 9.16. Sleep disorders; 9.17. Eating disorders; 9.18. Epilepsy and seizures; 9.19. Electroconvulsive therapy; 9.20. Brain stimulation; X. Neurodegeneration: 10.1. A neurodegenerative cascade of causality; 10.2. Prodromal disease and mild cognitive impairment; 10.3. Preclinical stages of neurodegenerative disease; 10.4. Spectra, domains and dimensions of neurodegenerative disease; 10.5. Reserve, resilience and resistance to neurodegeneration; 10.6. Environmental causes of neurodegenerative disease; 10.7. Morbidity and dual pathology in neurodegenerative disorders.