Vascular Ion Channels in Physiology and Disease

Foreword.- Endothelial cell ion channel expression and function in arterioles and resistance arteries.- Contribution and Regulation of Calcium channels in Endothelial Cells.- Mitochondrial depolarization in endothelial and other vascular cells and their role in the regulation of cerebral vascular tone.- Ion channels in Hypertension and Control of Blood Flow: Electrical conduction along endothelium of resistance arteries.- Ca2+/calmodulin-gated small- and intermediate-conductance KCa channels in cardiovascular regulation: Targets for novel pharmacological treatments.- Regional Variation in Arterial Myogenic Responsiveness - Links to Potassium Channel Diversity/Function.- Ion Channel Trafficking and Control of Arterial Contractility.- Abnormalities of Vascular Ion Channels during Hypertension.- Kv7 Potassium Channels as Therapeutic Targets in Cerebral Vasospasm.- Lysosomal Transient Receptor Potential Mucolipin (TRPML) Channels in Vascular Regulation and Diseases.- CalciumMobilization via Intracellular Ion Channels, Store Organization and Mitochondria in Smooth Muscle.- Role of mechanosensitive TRP channels in Abnormal Vasculature of Tumors.- TRPC and Orai channels in store-operated calcium entry and vascular remodeling.- Smooth muscle cell ion channels in pulmonary arterial hypertension: pathogenic role in pulmonary vasoconstriction and vascular remodeling.- Physiological roles and cholesterol sensitivity of endothelial inwardly-rectifying K+ channels: specific cholesterol-protein interactions through non annular binding sites.- Membrane lipids and regulation of smooth muscle ion channels.- Transient receptor potential channels in metabolic syndrome-induced coronary artery disease.- Mitochondrial ion channels in metabolic disease.- Index.