The discovery of mammalian nitric oxide (NO) synthesis from L-arginine has led to a profound increase in our understanding of basic physiological and pathophysiological processes. The NO-dependent regulation of steroidogenic cytochromes P450, such as aromotase, and local, tissue-specific regulation of NOS isoform expression by sexual steroid hormones, such as estrogen and progesterone, promises to provide new insights into the regulation of endocrinological processes. Research on the interaction between the NO and sexual steroid systems are likely to lead to novel therapeutic concepts for use in diseases associated with perturbations of the endocrine system.
Reihe
Sprache
Verlagsort
Verlagsgruppe
Illustrationen
43 s/w Abbildungen
XIV, 310 p. 43 illus.
Dateigröße
ISBN-13
978-3-662-03503-0 (9783662035030)
DOI
10.1007/978-3-662-03503-0
Schweitzer Klassifikation
1 Nitric Oxide Synthase Isoforms and Nitric Oxide Biosynthesis.- 2 Interaction of Nitric Oxide with Iron-Dependent Enzymes.- 3 Nitric Oxide and Cyclooxygenases.- 4 Hypoxia, Nitric Oxide and Vasoactive Gene Transcription.- 5 Nitric Oxide and Ovarian Steroidogenesis.- 6 Regulation of Uterine and Cervical Function by Nitric Oxide.- 7 Nitric Oxide in Arthritis: It's Probably There But What's It Doing?.- 8 Nitric Oxide and the Skeleton.- 9 Regulation of Endothelial Nitric Oxide Synthase by Estrogen.- 10 Estrogen, Nitric Oxide, and Primate Atherosclerosis.- 11 Nitric Oxide Deficiency in Preeclampsia.- 12 Endothelial Cells, Estrogen and Angiogenesis.- Previous Volumes Published in this Series.
