Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules

1. Microbial Fraction Library: A Screening Source for Drug Discovery.- 2. Efficient Total Synthesis of Omura Natural Products.- 3. Enantioselective Total Synthesis of the Antitumor Polycyclic Natural Products, FR182877 and Taxol.- 4. Synthetic Approaches on the Pluramycin-class Antibiotics.- 5. Recent Progress Toward the Total Synthesis of Duocarmaycins A and SA, Yatakemaycin, and PDE-I and -II.- 6. Structure-Activity Relationship Studies of Maitotoxin Based on Chemical Synthesis.- 7. Substitution of Allylic Picolinates with Various Copper Reagents and Synthetic Applications.- 8. Total Synthesis of Ingenol.- 9. Strategies for Synthesis of Anti-inflammatory Metabolites of Unsaturated Fatty Acids.- 10. Biosynthesis, biological functions, and receptors of leukotriene B4 and 12(S)-hydroxyheptadecatrienoic acid.- 11. Synthesis of classical/non-classical hybrid cannabinoids and related compounds.- 12. Exploring bioactive marine natural products and identification of their molecular targets.- 13. Target protein chemical modification.- 14. Target Identification of Bioactive Compounds by Photoaffinity Labeling Using Diazido Probes