The first edition of this book was well received by readers and reviewers and we are very grateful for the positive reactions. We were convinced then, and even more now, that MRI and MRS have much to offer in diagnosis, therapy monitoring and research of hereditary and acquired myelin disorders. In the last few years, a great deal of new information has come available, concern ing the genetic basis of inborn errors of metabolism and neurodegenerative disor ders, the role of subcellular structures, the enzyme biochemistry, the pathophysio logical mechanisms of posthypoxic-ischemic cerebral damage, and the inflammato ry processes in infectious and inflammatory disorders. MR images of many rare disorders have become available, either in our own experience or published by other groups. MR spectroscopy could confirm its role in certain clinical applica tions. Because of these developments, it was necessary for us to rewrite the book almost completely. In some fields developments are so fast that we may not have caught all the latest developments. The pattern of the new approaches has, however, been established, making the assimilation of newly available information easy. We are extremely grateful for the help of colleagues to make this book as com plete as possible. The positive reactions of those from whom we requested MR pictures or other forms of support were of enormous encouragement to us during our efforts to complete this project. We hope this work will be as warmly welcomed by our colleagues as the first edition.
Rezensionen / Stimmen
"This book should receive very positive reactions, even more than the first edition. We are indebted to the authors for this magnificent work." European Neurology
Auflage
Sprache
Verlagsort
Verlagsgruppe
Illustrationen
1249
1249 s/w Abbildungen
XI, 558 p. 1249 illus.
ISBN-13
978-3-662-03078-3 (9783662030783)
DOI
10.1007/978-3-662-03078-3
Schweitzer Klassifikation
1 Myelin and White Matter.- 2 Classification of Myelin Disorders.- 3 Selective Vulnerability.- 4 Myelination and Retarded Myelination.- 5 Lysosomes and Lysosomal Disorders.- 6 Metachromatic Leukodystrophy.- 7 Multiple Sulfatase Deficiency.- 8 Globoid Cell Leukodystrophy: Krabbe's Disease.- 9 GM1 Gangliosidosis.- 10 GM2 Gangliosidosis.- 11 Fabry's Disease.- 12 Fucosidosis.- 13 Mucopolysaccharidoses.- 14 Peroxisomes and Peroxisomal Disorders.- 15 Zellweger Cerebrohepatorenal Syndrome, Neonatal Adrenoleukodystrophy, and Infantile Refsum Disease.- 16 Rhizomelic Chondrodysplasia Punctata.- 17 Zellweger-like Syndrome.- 18 Pseudo-neonatal Adrenoleukodystrophy, Trifunctional Protein Deficiency, and Pseudo-Zellweger Syndrome.- 19 X-linked Adrenoleukodystrophy.- 20 Mitochondria and Mitochondrial Disorders.- 21 Defects of Mitochondrial DNA.- 22 Leigh Syndrome.- 23 Pyruvate Carboxylase Deficiency.- 24 Cerebrotendinous Xanthomatosis.- 25 Refsum Disease.- 26 Nucleus, DNA, and DNA Repair.- 27 Cockayne's Disease.- 28 Pelizaeus-Merzbacher Disease.- 29 18q? Syndrome.- 30 Phenylketonuria.- 31 Glutaric Aciduria Type 1.- 32 Propionic Acidemia.- 33 Hyperprolinemia.- 34 Nonketotic Hyperglycinemia.- 35 Maple Syrup Urine Disease.- 36 Canavan's Disease.- 37 L-2-Hydroxyglutaric Aciduria.- 38 Hyperhomocysteinemias.- 39 Urea Cycle Defects.- 40 Galactosemia.- 41 Sjögren-Larsson-Syndrome.- 42 Lowe Syndrome.- 43 Wilson Disease.- 44 Neuronal Ceroid Lipofuscinoses.- 45 Alexander's Disease.- 46 Myotonic Dystrophy.- 47 Congenital Muscular Dystrophy.- 48 Infantile-Onset Leukoencephalopathy with Swelling and a Discrepantly Mild Clinical Course.- 49 Childhood Ataxia with Diffuse Cerebral Hypomyelination.- 50 Leukoencephalopathy, Cerebral Calcifications, and Chronic Cerebrospinal FluidLymphocytosis (Aicardi-Goutières Syndrome).- 51 Inflammatory and Infectious Disorders.- 52 Multiple Sclerosis.- 53 Conditions Mimicking Multiple Sclerosis on MRI.- 54 Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Encephalomyelitis.- 55 Acquired Immunodeficiency Syndrome.- 56 Progressive Multifocal Leukoencephalitis.- 57 Subacute Sclerosing Panencephalitis.- 58 Progressive Rubella Panencephalitis.- 59 Toxic Encephalopathy.- 60 Central Pontine and Extrapontine Myelinolysis.- 61 Marchiafava-Bignami Syndrome.- 62 Posthypoxic-Ischemic Damage.- 63 Posthypoxic-Ischemic Leukoencephalopathy of Neonates.- 64 Delayed Posthypoxic Leukoencephalopathy of Maturity.- 65 Sub cortical Arteriosclerotic Encephalopathy.- 66 Vasculitis.- 67 Leukoencephalopathy After Chemotherapy and/or Radiotherapy.- 68 Cerebral Edema and Fluid Compartments in the CNS.- 69 Wallerian Degeneration and Myelin Loss Secondary to Neuronal and Axonal Degeneration.- 70 Pattern Recognition in White Matter Disorders.- 71 Magnetic Resonance Spectroscopy, Basic Principles, and Application in Myelin Disorders.- Acknowledgements.- References.
