Today microdialysis is a routine technique for monitoring the chemistry of tissues and organs in physiological and pharmacological research on animals. In more than 8000 papers microdialysis is used to uncover physiological mechanisms and the influence of drugs in almost every organ of the body. Since the first papers describing microdialysis in the human brain and peripheral tissues (1, 2) there are close to 1000 papers published on microdialysis in man and microdialysis has become a technique for routine monitoring of energy metabolism especially in neurointensive care (3, 4). This paper gives an account of the microdialysis technique describing its practical use and interpretation in monitoring energy metabolism and ischemia in human brain and peripheral tissues.
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ISBN-13
978-3-89967-124-7 (9783899671247)
Schweitzer Klassifikation
1 - Contents [Seite 6]
2 - Preface [Seite 8]
3 - Microdialysis in Neurointensive Care - Principles and Interpretations [Seite 9]
4 - Intracerebral Microdialysis during Routine Neuro Intensive Care [Seite 24]
5 - Microdialysis in Patients with Aneurysmal Subarachnoid Hemorrhage [Seite 36]
6 - Prediction of Secondary Brain Injury during Neurocritical Care: The Role of Cerebral Microdialysis [Seite 46]
7 - Myocardial Metabolism during Open Heart Surgery Assessed by Microdialysis [Seite 57]
8 - Technique and Results of Intraperitoneal Microdialysis ( IPM) [Seite 68]
9 - Initial Experience in Experimental and Clinical Use of Microdialysis in Liver Transplantation [Seite 72]
10 - Splanchnic Region in Critical Illness - Intestinal Microdialysis as a Tool for Regional Metabolic Monitoring [Seite 94]
11 - Tissue Pharmacokinetics of Antimicrobial Agents in Septic Patients [Seite 110]
12 - Tissue Metabolism in Different Types of Shock - Does Metabolic Monitoring make Sense? [Seite 118]
13 - List of Contributors [Seite 138]