The Challenge of Finding New Insecticides for a Mature Market.- The Biochemical Mode of Action of Insecticides.- Can Mode of Action Studies Guide Chemical Synthesis?.- Prospects of Exploitation of Insect Antijuvenile Hormones for Selective Insect Control.- Insecticides as Inhibitors of Respiration.- The Action of Spider Toxins on the Insect Nerve-Muscle System.- Interaction of Low-Molecular-Weight Effectors with Components of the Nicotinic Cholinergic Synapse: Triphenylmethylphosphonium and Phencyclidine as Inhibitors of Acetylcholinesterase.- Neurochemistry of Cholinergic Synapses in Insects.- Glutamate and GABA Receptors of Insect Muscles: Biochemical Identification and Interactions with Insecticides.- Biogenic Amines and Second Messenger Systems in Insects.- Neuropeptides in Insects: Possible Leads to New Control Methods.