1. Introduction
2. From Biological Chemistry to Bioorthogonal Reactions
3. Strain-Promoted Bioorthogonal Chemistry
4. Metal Catalysis in Live Environments
5. Artificial Metalloenzymes In Vivo
6. Bioorthogonal Nanozymes for Catalysis in Living Systems
7. Photocatalysis in Chemical Biology
8. Bioorthogonal Supramolecular Assemblies in Cells
9. Biomimetic Nanozymes
10. Protein Modification through Metabolic Incorporation of Noncanonical Amino Acids
11. Bioorthogonal Tools for the Synthesis, Modification, and Analysis of Lipids
12. Bioorthogonal Chemistry of Nucleic Acids
13. Abiotic Chemistry in Living Animals: Therapeutic Applica>t
14. Bioorthogonal Strategies for the Uncaging and Assembly of Drugs