GPCRs

Part I GPCR structure1. Progress in GPCR structure Determination2. Structure, function and therapeutic potential of adhesion GPCRs3. Structural diversity in ligand recognition by GPCRs4. NMR-based approaches to the study of GPCRs and GPCR-ligand interactions5. Supramolecular structure of opsins6. Molecular determinants of GPCR oligomerization7. Structure of G-protein-coupled receptor heteromers8. Class A GPCR oligomerization: reasons of controversy Part II GPCR function9. Quantifying GPCR allostery and biased signaling10. Kinetics of ligand binding and signaling11. Allosteric modulators targeting GPCRs12. Arrestin-mediated signaling at GPCRs13. Organellar Gb¿ signaling - GPCR signaling beyond the cell surface Part III GPCRs in disease and targeted drug discovery14. G protein-coupled receptor allosteric modulators: understanding modulator affinity and pharmacological dose15. Computer-aided GPCR drug discovery16. Tackling the complexities of orphan GPCR ligand discovery with rationally assisted approaches17. G protein-coupled receptors in neurodegenerative diseases18. GPCR targets in type 2 diabetes19. GPCRs in thromboinflammation and hemostasis20. Angiotensin II receptors: structure-function and drug discovery21. GPCRs in innate and adaptive immune responses22. Role of GPCRs in cancer