Organoselenium Compounds in Biology and Medicine

An overview of organoselenium chemistry: From fundamentals to Synthesis;

Looking Beyond the traditional Idea of Glutathione Peroxidase Mimics as Antioxidants;

Synthesis of organoselenium compounds with potential biological activities;

The Relevant Chemistry of Imidazoline-2-selone Donors with potential Biological Applications;

Organoselenium cations: Structures, reactivity and applications;

Organoselenium flurophores for probing ROS and heavy metals;

Non-bonded selenium...heteroatom interactions in selenoenzymeglutathioneperoxidase (GPx) and mimics;

Carbohydrate-derived Organoselenium Compounds: Synthesis and Application in the Structural Analysis of Biomolecules;

Reaction of Selenium compounds with reactive oxygen species and the controlof oxidative stress;

Reactive selenium species: Redox modulation, antioxidant, antimicrobial and anticancer activities;

Ebselen and thioredoxin systems in human health, disease and therapeutic potential;

History and development of selenium based radioprotectors: Distinction between inorganic vs. organic forms;

Toxicology and anticancer activity of synthetic organoselenium compounds;

Metabolism of selenium/selenocystine and their roles in the prevention and treatment of human cancer;

Organoselenium compounds as cancer therapeutic agents;

Cancer prevention by different forms of selenium