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This well-accessible textbook constitutes a practical guide to metabolomics approaches and applications in an integrative manner.
Illustrated by numerous real-life examples and case studies the book teaches how to set up and carry out metabolomics experiments, from sample collection to storage techniques, and guides the reader through the potentials and challenges of metabolite analysis. In addition, this textbook shows how to obtain insights into molecular mechanisms deployed in different physiological contexts (e.g., exercise, healthy ageing) as well as in different (metabolic) diseases, be it Diabetes, Cancer, Alzheimer´s Disease, Asthma or others. The book brings together knowledge from biochemical, biological, and medical aspects, and further equips the reader with know-how from sample collection and handling to data processing, analysis and interpretation.
This textbook is a must-have for advanced undergraduates and graduate students interested in applied biochemistry and metabolomics, as well as for instructors who teach courses in biomedicine, physiology or biochemistry.
Julijana Ivanisevic is a Head of the Metabolomics Unit and a Senior Lecturer at the Faculty of Biology and Medicine, University of Lausanne (UNIL), Switzerland. She joined UNIL in 2015 following her postdoctoral training at the Center for Metabolomics and Mass Spectrometry, the Scripps Research Institute (SD, CA). She received her PhD in chemical biology at the Aix-Marseille University, France, in 2011.
Martin Giera is associate professor and head of the Metabolomics Group at the Leiden University Medical Center (LUMC). After studying pharmaceutical sciences in Heidelberg and Munich, becoming a licensed pharmacist, he obtained his Ph.D. degree from Ludwig-Maximilians Universität München (LMU) in pharmaceutical chemistry and did international postdoctoral training at the VU University Amsterdam. He was an assistant professor at the VU University Amsterdam, visiting scientist at Harvard Medical School and visiting professor at the Scripps research institute. Dr. Giera is an internationally renowned expert in metabolomics, lipidomics, lipid mediator analysis, and bioactivity testing. Dr. Giera has been a DAAD fellow (The German Academic Exchange Service) and was a permanent member and chairman of the interdisciplinary committee of FWO (Flanders Science Foundation). He was Guest Editor for several journals and is on the editorial board of Metabolites (MDPI) and serves on the scientific advisory board of Cell Star Protocols. Dr. Giera is coordinator of the multi-national H2020 ITN consortium ArthritisHeal and track chair at the SLAS 2021 conference. His group is internationally renowned for its work on clinical lipidomics and metabolomics. Next to several national and international collaborations his group also has strong ties to national companies and international partners with Dr. Giera being a consultant to several industry partners.
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