Pancreatic Cancer and Periampullary Neoplasms, An Issue of Surgical Clinics of North America

Name: Pancreatic Cancer and Periampullary Neoplasms, An Issue of Surgical Clinics of North America
Brand: Elsevier
Price: 86.86 EUR
Availability: OnlineOnly

Jeffrey M. Hardacre(Autor*in)

Elsevier (Verlag)

1. Auflage

Erschienen am 21. November 2016

100 Seiten

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Inhalt

Intro
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Genetics of Pancreatic Cancer and Its Implications on Therapy
Key points
Introduction
Genetics of pancreas cancer
Pancreas cancer and therapeutic targets
Future directions
Screening for Pancreatic Cancer
Key points
Introduction
Epidemiology and risk factors for familial pancreatic cancer
Genetic predisposition for pancreatic cancer
Screening and surveillance of pancreatic cancer
Management of detected pancreatic lesions in asymptomatic high-risk individuals
Summary
Imaging Evaluation of Pancreatic Cancer
Key points
Introduction
Imaging techniques and protocols
Imaging features of solid pancreatic neoplasms
Classification of resectable, borderline resectable, and locally advanced/nonresectable pancreatic ductal adenocarcinoma
Standardization of radiologic reporting for pancreatic ductal adenocarcinoma
Summary
Endoscopic Evaluation in the Workup of Pancreatic Cancer
Key points
Introduction
Clinical presentation
Diagnostic modalities
Transabdominal ultrasound imaging
Cross-sectional imaging: computed tomography and MRI
Role of endoscopy in diagnosis of pancreatic cancer
Pretreatment staging of pancreatic cancer
Summary
Surgical Therapy for Pancreatic and Periampullary Cancer
Key points
Introduction
Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy
Pancreaticoduodenectomy with standard versus extended lymphadenectomy
Pancreatic reconstruction
Superior mesenteric artery first approach
Minimally invasive pancreatectomy
Enhanced recovery after surgery for pancreaticoduodenectomy
Summary
Adjuvant and Neoadjuvant Therapy for Resectable Pancreatic and Periampullary Cancer
Key points
Introduction
Pancreatic adenocarcinoma
Periampullary carcinoma
Summary
Enhanced Recovery Pathways in Pancreatic Surgery
Key points
Introduction
Studies on enhanced recovery after surgery protocols in pancreatic surgery
Facets of enhanced recovery after surgery protocols in pancreatic surgery
Summary
Postpancreatectomy Complications and Management
Key points
Introduction
Pancreatic fistula
Delayed gastric emptying
Postpancreatectomy hemorrhage
Summary
Definition and Management of Borderline Resectable Pancreatic Cancer
Key points
Introduction
Identification of borderline resectable patients
Imaging
Definitions of resectability
Management
Surgical technique
Summary
Techniques of Vascular Resection and Reconstruction in Pancreatic Cancer
Key points
Introduction
Preoperative planning
Surgical approach
Postoperative care
Summary
Management of Locally Advanced Pancreatic Cancer
Key points
Introduction
Criteria for unresectability
Treatment algorithm
Chemoradiation therapy
Role of surgery: resection and electroporation
Local ablative therapies
Irreversible electroporation
Summary
Management of Metastatic Pancreatic Adenocarcinoma
Key points
Introduction
First-line systemic therapy
Second-line systemic therapies
Novel therapeutics
Antistromal agents
Immune therapies
Vaccines
Checkpoint blockade
CD40 agonists
Supportive and palliative care
Summary
Palliative Care for Pancreatic and Periampullary Cancer
Key points
Introduction
Goals and outcomes of palliative care
Obstructive jaundice
Gastric outlet obstruction
Pain management
Other issues in pancreatic cancer
End-of-life care and the role of hospice
Summary
Intraductal Papillary Mucinous Neoplasm of the Pancreas
Key points
Introduction
Biology of intraductal papillary mucinous neoplasms
Diagnosis
Clinical management
Follow-up strategy
Adjuvant therapy
Summary
Surgical Management of Pancreatic Neuroendocrine Tumors
Key points
Introduction
Pathophysiology
Classification and staging
Clinical presentation and diagnosis
Surgical management
Summary
Index

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