Nucleic Acids: A Natural Target for Newly Designed Metal Chelate Based Drugs discusses how human diseases are becoming more costly to treat, along with updates on the resistance offered by disease-causing agents. The abundance of drugs in the market has provided great relief to patients, but side effects can destroy the immune system of the body. Patients need to boost their immune system, and at the same time cover expenses incurred to cure disease. Thus, a paradigm shift is needed to design a drug molecule with low cost and easy availability.
Metal complexes can be a great example of such a shift, as metal ions are components of biological molecules and can achieve good binding capability to specific targets while not allowing them to damage healthy cell system. Therefore, in this book, a comprehensive compilation of recent data is provided, including the structural elucidation of metal complexes by advanced techniques and the binding pattern of metal complexes with specific targets.
- Focuses on recent advances and methods adopted for generating new metal-based molecules and their interactions with biomolecules, especially nucleic acids
- Addresses challenges for developing new metal-based drugs
- Examines advances in optical techniques for the characterization of metal-based drugs
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Illustrationen
150 illustrations (60 in full color)
Dateigröße
ISBN-13
978-0-12-820504-4 (9780128205044)
Schweitzer Klassifikation
1. Zinc complexes and their interaction with nucleic acids and other biomolecule targets 2. Ruthenium complexes: An insight into their interactions with nucleic acids and biomolecules 3. Nucleic acid interactions of copper chemotherapeutics 4. Recent advances in iron complexes and their interaction with nucleic acids 5. Manganese complexes: their interaction studies with nucleic acids and biomolecules
