Structure, Function and Modulation of Neuronal Voltage-Gated Ion Channels

Preface.
Contributors.
PART 1 NEURONAL VOLTAGE-GATED ION CHANNEL FUNCTIONS.
1 Neuronal L-Type Voltage-Gated Calcium Channels (AlexanderScriabine and David J. Triggle).
2 Voltage-Gated N-Type and T-Type Calcium Channels andExcitability Disorders (Elizabeth Tringham and Terrance P.Snutch).
3 Voltage-Gated Sodium Channels: Multiple Roles in thePathophysiology of Pain (Sulayman D. Dib-Hajj, Bryan C. Hains,Joel A. Black, and Stephen G. Waxman).
4 The Role of Ion Channels in the Etiology and Development ofGliomas (Amy K. Weaver and Harald Sontheimer).
5 Shaker Family Kv1 Voltage-Gated Potassium Channels inMammalian Brain Neurons (Helene Vacher and James S.Trimmer).
6 Unique Mitochondrial Ion Channels: Roles in SynapticTransmission and Programmed Cell Death (Elizabeth A.Jonas).
7 Regulation of Neuronal Excitability by the Sodium-ActivatedPotassium Channels Slick (SLO2.1) and Slack (SLO2.2) (ValentinK. Gribkoff and Leonard K. Kaczmarek).
PART 2 MODULATORY MECHANISMS AND INFLUENCES ON NEURONALVOLTAGE-GATED ION CHANNEL FUNCTION.
8 Alternative Splicing of Neuronal Cav2 Calcium Channels(Diane Lipscombe, Summer E. Allen, Annette C. Gray, SpiroMarangoudakis, and Jesica Raingo).
9 Effect of Hypoxia/Ischemia on Voltage-Dependent Channels(Xiang Q. Gu, Hang Yao, and Gabriel G. Haddad).
10 In Vivo Roles of Ion Channel Regulatory Protein Complexes inNeuronal Physiology and Behavior (Smitha Reddy, MohammadShahidullah, and Irwin B. Levitan).
11 Regulation of Neuronal Ion Channels by G-Protein-CoupledReceptors in Sympathetic Neurons (Mark S. Shapiro and NikitaGamper).
12 BK Channels: Regulation of Expression and PhysiologicalImpact (P. Kundu, A. Alioua, Y. Kumar, R. Lu, J. Ou, E.Sanchez-Pastor, M. Li, E. Stefani, and L. Toro).
13 Structural Basis for Auxiliary KChIP Modulation of Kv4Channels (KeWei Wang and Jijie Chai).
PART 3 DRUG DISCOVERY TARGETS AND TECHNOLOGY.
14 Sodium Channel Blockers for the Treatment of Chronic Pain(Mark R. Bowlby and Edward Kaftan).
15 Neuronal Kv7 Potassium Channels as Emerging Targets for theTreatment of Pain (Steven I. Dworetzky and Valentin K.Gribkoff).
16 Small-Molecule Modulators of Large-Conductance,Calcium-Activated (BK) Channels (John E. Starrett Jr.).
17 High-Throughput Screening Technologies in Ion Channel DrugDiscovery (Edward B. Stevens, Andrew D. Whyment, and J. MarkTreherne).
Index.