Electron Paramagnetic Resonance

Name: Electron Paramagnetic Resonance | Volume 21
Brand: Royal Society of Chemistry
Price: 412.99 EUR
Availability: OnlineOnly

Volume 21

Bruce C. Gilbert(Herausgeber*in)

Royal Society of Chemistry (Verlag)

1. Auflage

Erschienen am 19. Dezember 2008

350 Seiten

E-Book

PDF mit Wasserzeichen-DRM

Systemvoraussetzungen

978-1-84755-888-6 (ISBN)

412,99 €inkl. 7% MwSt.

Systemvoraussetzungen

für PDF mit Wasserzeichen-DRM

E-Book Einzellizenz

Als Download verfügbar

Zur neuen Auflage

Beschreibung

Weitere Details

Weitere Ausgaben

Person

Inhalt

Electron Paramagnetic Resonance
CONTENTS
Preface
Biomedical applications of EPR spectroscopy
Introduction
Reactive oxygen species
Reactive nitrogen species
Consequences of free radical reactions with biomolecules
Damage to lipids
Damage to DNA
Damage to proteins
Free radicals and disease
Cancer
Infectious disease
Alzheimers disease
Diabetes
Cardiovascular disease
Miscellaneous conditions
Selected biomedical EPR techniques
In vivo EPR oximetry
In vivo EPR imaging
References
EPR studies of radiation damage to DNA and related molecules
Introduction
Scope of this report
Recent trends in DNA radiation chemistry
Symbols used
DNA constituents
Single crystal studies
Amorphous systems
DNA
Track structure in DNA irradiated with heavy ions
Studies of DNA-iron complexes
Formation of 8-oxo-G in irradiated DNA by multiple one-electron oxidations
Electron transfer versus differential fading of radicals
Role of excited states in DNA damage-experimental and theoretical results
Photoinduced radical formation in DNA
DNA yields and strand breaks
Electron induced cleavage of thymine dimers
Acknowledgements
References
Measurement of interspin distances by EPR
Introduction to distance determination
Related reviews
CW
Accessibility to paramagnetic relaxation reagents
Relaxation of free radicals due to nearby paramagnetic metals
DEER (PELDOR)
Determination of relative orientations of radicals in DEER
More than two spins
Uncertainty in distributions
Metal-metal distances by DEER
Limitations of the DEER method
Examples of applications of DEER
Other spin echo methods
DQC and DEER
Out-of-phase echo detection
Biological studies at room temperature
Sample preparation limitations
Acknowledgements
References
Time-resolved electron paramagnetic resonance studies of transient organic radicals
Introduction
Photochemical applications
Photoionization
Photoreduction of sensitizers
Photooxidation
Homolytic bond scission
Addition reactions to double bonds
CIDEP studies
Pulse radiolysis EPR
Concluding remarks
References
EPR of paramagnetic centres on solid surfaces
Introduction
s-Block metal oxides
Transition metal oxides
TiO2
ZrO2
CeO2
V2O5 Oxides
CrOx Oxides
MoOx Oxides
Iron oxides
Copper oxides
ZnO
p-Block metal oxides
References
EPR of exchange coupled oligomers
Introduction
p-Block
d-Block
Dimetallic complexes
Trimetallic complexes
Tetrametallic complexes
Polymetallic complexes
Polymetallic cores encapsulated into polyoxometalates
Molecular wheels
Single-molecule magnets (SMMs)
Mixed p/d- and d/f-block
Biological systems
Methods
Nitrogenases
Copper
Manganese (excluding photosystems)
Diiron (including 2Fe2S)
Other iron-sulfur centres
Coupled haems
Cobalt
Photosystems
Nickel
References
Continuous wave and pulsed EPR analyses of metalloproteins
Introduction
Field-swept EPR methods
Detecting nuclear interactions
Now you see it, now you don't
Interpretation of EPR data
Choosing between different experiments
Example 1. The study of high-spin ferric heme proteins
Example 2. The nickel-containing methyl-coenzyme M reductase
Conclusion
Acknowledgements
References
An EPR tool box for exploring the formation and properties of ordered template mesoporous materials
Introduction
Templated mesoporous materials
The formation mechanism of TMM
General principles
Methods for mechanistic studies
The formation of TMM with ionic templates
The formation of TMM with non-ionic templates
The EPR tool box
Spin-probes
The EPR experiments
EPR investigation of the formation of TMM
The location of the nitroxide label in micelles
EPR studies of MCM-41
EPR studies of SBA-15
Studies of cubic mesoporous materials
Studies of wormlike mesoporous materials
Summary and outlook
Acknowledgements
References
High-field pulse EPR instrumentation
Introduction
Scope of the review
High-field EPR spectroscopy
History of high-frequency pulse EPR
Sensitivity
Cavities
Sensitivity and deadtime
Measurement bandwidth
Averaging and pulse repetition time
St Andrews system design
Current system performance
System overview
Induction mode cavities and sample holders
Pulse sources and pulse generation
Phase coherent detection system
Spectrometer front end system design
Control software
Discussion
Fourier transform EPR and FID detection
Hyperfine and electron-dipolar spectroscopies
Dynamic nuclear polarisation (DNP)
Conclusions and outlook
References

Systemvoraussetzungen

Als PDF speichern Als Link merken