Innate Tolerance in the CNS

Preface.- Section I. Comparative Physiology and Historical Background.- 1. Tolerance, Historical Review.- 2. Anoxia resistance in lower and higher vertebrates.- 3. Hibernation: A Natural Model of Tolerance to Cerebral Ischemia/Reperfusion.- 4. Preconditioning in the Heart.- Section II. Conditioning Methods.- 5. Neuroprotection and Physical Preconditioning: Exercise, Hypothermia, and Hyperthermia.- 6. A New Future in Brain Preconditioning Based on Nutraceuticals: Focus on a-Linolenic Omega-3 Fatty Acids for Stroke Protection.- 7. Medical Gases for Conditioning: Volatile Anesthetics, Hyperbaric Oxygen, and Hydrogen Sulfide.- 8. Hypoxic Preconditioning in the CNS.- 9. Pharmacologic Preconditioning.- 10. Surgical Methods to Induce Brain Preconditioning.- Section III. Conditioning Models for Cerebral Ischemia.- 11. Tolerance Against Global Cerebral Ischemia: Experimental Strategies, Mechanisms, and Clinical Applications.- 12. Preconditioning and Neuroprotection in the Immature Brain.- 13. Conditioning Studies in Focal Cerebral Ischemia: Model Selection, Physiological Monitoring, and Other Methodological Issues.- 14. Preconditioning for Subarachnoid Hemorrhage.- 15. Preconditioning for Intracerebral Hemorrhage.- 16. The Protective Effects of Ischemic Postconditioning in Experimental Stroke.- Section IV. Mechanisms of Preconditioning.- 17. Synaptic Signaling in Ischemic Tolerance.- 18.- The Genomics of Preconditioning and Ischemic Tolerance.- 19. How do Subcellular Organelles Participate in Preconditioning-Conferred Neuroprotection?.- 20. Ischemic Preconditioning-Mediated Signaling Pathways Lead to Tolerance Against Cerebral Ischemia.- 21. Preconditioning the Neurovascular Unit: Tolerance in the Brain's Non-Neuronal Cells.- Section V. Other Neurological Disorders.- 22. Preconditioning for Surgical Brain Injury.- 23. Intrinsic Neuroprotection in Traumatic Brain Injury.- 24. Preconditioning for Epilepsy.- 25. Ischemic Pre- andPost-Conditioning in the Retina.- Section VI. Clinical Applications.- 26. Clinical Cerebral Ischemic Preconditioning.- 27. Preconditioning Strategy: Coronary Bypass, Subarachnoid Hemorrhage, Temporary Proximal Vessel Occlusion in Carotid Revascularization, and Intracranial Aneurysm Surgery.- 28. HBO preconditioning for TBI and Stroke Patients.- 29. Electroacupuncture Preconditioning for Stroke Patients.- 30. Clinical Trials of Ischemic Conditioning.- Epilogue.- Index.