Drug Related Encephalopathies

Name: Drug Related Encephalopathies
Brand: Nova Science Publishers Inc
Price: 185.99 EUR
Availability: OnlineOnly

Sechi GianPietro(Herausgeber*in)

Nova Science Publishers Inc

Erschienen am 4. Juni 2013

522 Seiten

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978-1-61668-047-3 (ISBN)

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Inhalt

Intro
DRUG RELATED ENCEPHALOPATHIES
DRUG RELATED ENCEPHALOPATHIES
Library of Congress Cataloging-in-Publication Data
Contents
Preface
About the Editor
Introduction
References
Chapter 1: Drug-Related Hyperthermic Encephalopathies
Abstract
Introduction
Pathophysiology of Thermoregulation
Neuroleptic Malignant Syndrome
Epidemiology
Genetic Predisposition
Pathophysiology
Clinical Characteristics
NMS vs Malignant Hyperthermia
Drugs and Hyperthermic Encephalopathies
Treatment of NMS
Conclusions
Parkinsonism-Hyperpyrexia Syndrome
Pathogenesis
Treatment
Serotonin Syndrome
Triggering Factors and Neurochemistry
Differential Diagnosis
Anticholinergic Intoxication
Baclofen Withdrawal Syndrome
Strychnine Poisoning
Cocaine Intoxication
Conclusions
References
Chapter 2: Encephalopathies Related to Antiepileptic Drugs
Abstract
Abbreviations
Introduction
"Old" Antiepileptic Drugs
Succinimides
"New" Antiepileptic Drugs
Transient Lesions in the Splenium of Corpus Callosum and Antiepileptic Drugs
Conclusions
References
Chapter 3: Ethanol-Related Encephalopathies
Abstract
Introduction
Responsible Brain Regions for Alcohol-Related Cognitive Impairment
Mechanisms of Alcohol-Induced Brain Damage
Importance of the Use of Human Alcoholic Brain Tissue and Non-Hypothesis Driven, High-throughput Analysis
Neuroproteomics of Human Alcoholic Brain
Conclusion
Acknowledgements
References
Chapter 4: Antimicrobial Agent-Induced Encephalopathy
Abstract
1. Introduction
2. Antibacterial Agents
3. Antiprotozoal and Antibacterial Agents
4. Other Encephalopathies Associated with Antimicrobial Agents
5. Antiviral Agents
Acknowledgment
References
Chapter 5: Encephalopathies Related to Abuse of Psychoactive Drugs
Abstract
Introduction
Categories of Abused Substances
Encephalopathy Linked to Abuse of Drugs
Diagnosis and Therapy of Encephalopathy
Cocaine Abuse and Encephalopathy
Amphetamine Abuse and Encephalopathy
Methcathinone
Hallucinogens
Narcotics
Inhalants
Anesthetics
Designer Drugs of the Future
Designer Drugs of the Future
References
Chapter 6: Cancer Chemotherapy-Related Encephalopathy
Abstract
Introduction
Neuro-Toxic Effects of External Beam Radiation Therapy
Neurotoxicity and the Cancer Chemotherapeutic Drugs
Conclusion
References
Chapter 7: Drug-Related Posterior Leukoencephalopathy
Abstract
Introduction
Risk Factors
Clinical Features
Imaging
Other Laboratory Findings
Differential Diagnosis
Pathophysiology
Treatment
Prognosis
Conclusions
References
Chapter 8: Steroid Encephalopathy: Steroid Psychosis and Dementia
Abstract
Introduction
Frequency and Character of Behavioral Symptoms
Steroid Withdrawal Syndrome
Steroid Dementia Syndrome
Potential Etiologic Mechanisms
Prevention and Treatment of Steroid-Induced Psychopathology
References
Chapter 9: Encephalopathies Related to Exogenous or Endogenous Benzodiazepines
Abstract
Introduction
1. GABA-A Receptor Structure and Function
2. The Peripheral Benzodiazepine Receptor (PBR)
3. GABA-A Benzodiazepine Binding Site: Agonists, Antagonists and Inverse Agonists
4. Clinical Effects of Benzodiazepines
5. Laboratory Assessment of Benzodiazepine-Related Encephalopathies
6. Management of Benzodiazepine-Related Encephalopathies
7. Role of "Endozepines? in other Brain Disorders
8. Endozepine Stupor: Where is it Now?
9. Conclusion
References
Chapter 10: Encephalopathies Related to Unconventional Therapies
Abstract
Introduction
CAM and Encephalopathy
1. Encephalopathy Due to Heavy Metal Toxicity or Poisoning
2. Encephalopathy Secondary to Adverse Effects of Herbal Medicine Use
Conclusion
References
Chapter 11: Approach to Reye and Reye-like Syndromes
Abstract
1. Background
2. Diagnosis of RS
3. Clinical Presentation of Reye Syndrome
4. Pathophysiology
5. Etiology of Reye Syndrome
6. Metabolic Diseases That Can Mimic Reye Syndrome
7. Genetics of Reye Syndrome
8. The Role of Exogenous Chemicals and Toxic Factors in Reye Syndrome
9. Aspirin and Reye Syndrome - Epidemiological Studies
10. Aspirin and Reye Syndrome - Mechanisms
11. Aspirin, Reye Syndrome, and Allergic Diseases
12. Diagnostic Algorithm for Reye Syndrome and Reye-like Syndrome
13. Prognosis of Reye Syndrome
14. Conclusion
References
Chapter 12: Neuroimaging in Drug-Related Encephalopathies
Introduction
Neuro-Imaging Modalities
Neuroimaging Characteristics of Various Drug Related Encephalopathies
Summary
References
Index

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