Introductory Comments
About the authors
Preface Meeting the Challenge of Patients with Immune Mediated Liver Disease
Keith D. Lindor, keith.lindor@asu.edu
Foreword: Contemporary Liver Immunology and Immunopathology: Obstacles and Opportunities
Ian R. Mackay, ian.mackay@monash.edu
Chapter 1: Core concepts in immunology
Cliona O'Farrelly & Derek Doherty
Chapter 2: The Geoepidemiology of Autoimmune Liver Disease
Carlo Selmi, Cecilia B. Chighizola, Angela Ceribelli, Maria De Santis, Pier Luigi Meroni, & Renqian Zhong
Chapter 3: Diagnostic Liver Immunology
Christopher Bowlus
Chapter 4: The Liver as a Lymphoid Organ
Percy Knolle
Chapter 5: Innate Immunity and Disorders of the Liver
Mathias Heikenwalder, Percy Knolle, & U. Protzer
Chapter 6: The Liver and Immune Tolerance
Zhigang Tian, Cai Zhang, & Zhe-Xiong Lian
Chapter 7: The Diagnosis and Classification of Immune Mediated Hepatic
Diseases
F. Alvarez
Chapter 8: The Diagnosis and Classification of Immune Mediated Biliary Diseases
Gideon Hirschfield
Chapter 9: Bacterial Infections in Liver
Eirini I. Rigopoulou, Daniel S. Smyk, Timoklia Orfanidou, Dimitrios Bogdanos, &
M. Eric Gershwin
Chapter 10: The Diagnosis and Classification of Parasitic Diseases of the Liver
Shyamapada Mandal & Manisha Mandal
Chapter 11: Viral Diseases of the Liver
Gadi Lalazar & Yaron Ilan
Chapter 12: Hepatitis A: Immune response and virus evolution
Rosa M. Pinto, Albert Bosch, & Gerardo Kaplan
Chapter 13: Immunopathogenesis of Chronic Hepatitis B and the Clinical
Events that Shape its Natural History
Stevan A. Gonzalez & Robert P. Perrillo
Chapter 14: Hepatitis C
Mario U. Mondelli, Stefania Varchetta, & Francesco Negro
Chapter 15: Immunopathogenesis of Hepatitis D
Sebastian Luneman, Jan Grabowski, & Heiner Wedemeyer
Chapter 16: Hepatitis E
Hiroki Takahashi & Mikio Zeniya
Chapter 17: Primary Biliary Cirrhosis
Pietro Invernizzi, Patrick S.C. Leung, Ma Xiong, & M. Eric Gershwin,
Chapter 18: Autoimmune Hepatitis
Diego Vergani, Rodrigo Liberal, & Giorgina Mieli-Vergani
Chapter 19: Primary Sclerosing Cholangitis
Harald Hofer, Emina Halibasic, Katharina Staufer & Michael Trauner,
Chapter 20: Overlap Syndromes
Said Al Mamari, Roger Chapman & Kirsten Muri Boberg,
Chapter 21: Alcoholic Liver Disease
Gyongyi Szabo
Chapter 22: Non-Alcoholic Fatty Liver Disease
Arun Sanyal & Vaishali Patel
Chapter 23: Pediatric Liver Disease
Giorgina Mieli-Vergani, Rodrigo Liberal & Diego Vergani
Chapter 24: Mechanisms of Acute Liver Failure
Christian Trautwein & Alexander Koch
Chapter 25: Non-Immune Mediated Drug Induced Hepatotoxicity
Christian Strassburg
Chapter 26: Immune-Mediated Drug Induced Liver Injury
Einar S. Bjornsson & Guruprasad Aithal
Chapter 27: The Immunopathogenesis of Cirrhosis
Bin Gao, Scott L. Friedman & Wajahat Z. Mehal
Chapter 28: Graft vs. Host Disease
John Vierling & Ali Raza
Chapter 29: Immune-mediated liver disease in the transplantated liver
Palak Jitendrakumar Trivedi, Ka-Kit Li & James Neuberger,
Chapter 30: The future of liver immunology
M. Eric Gershwin, John Vierling & Michael Manns
