Platelet Proteomics

Contributors.
Foreword.
Preface.
Acronyms.
PART I GENERAL OVERVIEW: PLATELETS, SAMPLE PREPARATION, ANDMASS SPECTROMETRY-BASED PROTEOMICS.
1 Platelets and Their Role in Thrombotic and CardiovascularDisease: The Impact of Proteomic Analysis (Ronald G. Stanley,Katherine L. Tucker, Natasha E. Barrett, and Jonathan M.Gibbins).
2 Mass-Spectrometry-Based Proteomics: General Overview andPosttranslational Modification Analysis in the Context of PlateletResearch (Julia Maria Burkhart and Albert Sickmann).
3 Sample Preparation Variables in Platelet Proteomics forBiomarker Research (Maria Zellner and Rudolf Oehler).
PART II ANALYSIS OF THE PLATELET PROTEOME: GLOBALAPPROACHES AND SUBPROTEOMES.
4 Two-Dimensional Gel Electrophoresis: Basic Principles andApplication to Platelet Signaling Studies (AngelGarcia).
5 The Platelet Membrane Proteome (Yotis A. Senis).
6 Proteomics of Platelet Granules, Organelles, and Releasate(James P. McRedmond).
7 The Platelet Microparticle Proteome (David M.Smalley).
8 N-Terminal Combined Fractional Diagonal Chromatographic(COFRADIC) Analysis of the Human Platelet Proteome (FrancisImpens, Kenny Helsens, Niklaas Colaert, Lennart Martens, JoelVandekerckhove, and Kris Gevaert).
PART III INTEGRATED "OMICS" AND APPLICATIONTO DISEASE.
9 Serial Analysis of Gene Expression (SAGE) For Studying thePlatelet and Megakaryocyte Transcriptome (Michael G.Tomlinson).
10 The Application of Microarray Analysis and Its Integrationwith Proteomics for Study of Platelet-Associated Disorders(Dmitri V. Gnatenko and Wadie F. Bahou).
11 Platelet Functional Genomics (Isabelle I. Salles, Marie N.O'Connor, Daphne C. Thijssen-Timmer, Katleen Broos, and HansDeckmyn).
12 Systems Biology to Study Platelet-Related Bleeding Disorders(Jan-Willem N. Akkerman and Bernard De Bono).
13 Platelet Proteomics in Transfusion Medicine (ThomasThiele, Leif Steil, Uwe V¨olker, and AndreasGreinacher).
14 Cardiovascular Proteomics (Fernando Vivanco, Fernando dela Cuesta, Maria G. Barderas, Irene Zubiri, and GloriaA´lvarez-Llamas).
Index.