Paves the way for new industrial applications using redox biocatalysis
Increasingly, researchers rely on the use of enzymes to perform redox processes as they search for novel industrial synthetic routes. In order to support and advance their investigations, this book provides a comprehensive and current overview of the use of redox enzymes and enzyme-mediated oxidative processes, with an emphasis on the role of redox enzymes in chemical transformations. The authors examine the full range of topics in the field, from basic principles to new and emerging research and applications. Moreover, they explore everything from laboratory-scale procedures to industrial manufacturing.
Redox Biocatalysis begins with a discussion of the biochemical features of redox enzymes as well as cofactors and cofactor regeneration methods. Next, the authors present a variety of topics and materials to the research and development of full-scale industrial applications, including:
* Biocatalytic applications of redox enzymes such as dehydrogenases, oxygenases, oxidases, and peroxidases
* Enzyme-mediated oxidative processes based on biocatalytic promiscuity
* All the steps from enzyme discovery to robust industrial processes, including directed evolution, high-throughput screening, and medium engineering
* Case studies tracing the development of industrial applications using biocatalytic redox reactions
Each chapter ends with concluding remarks, underscoring the key scientific principles and processes. Extensive references serve as a gateway to the growing body of research in the field.
Researchers in both academia and industry will find this book an indispensable reference for redox biotransformations, guiding them from underlying core principles to new discoveries and emerging industrial applications.
Auflage
Sprache
Verlagsgruppe
Produkt-Hinweis
Dateigröße
ISBN-13
978-1-118-40932-9 (9781118409329)
Schweitzer Klassifikation
Daniela Gamenara, PhD, is Assistant Professor in theOrganic Chemistry Department of the Faculty of Chemistry ofUniversidad de la República, Uruguay. After two shortpostdoctoral internships, her current scientific interest is thedevelopment of enzymatic methodologies for the synthesis of highadded-value compounds and natural products as well, together withthe use of new trends in organocatalysis for the same purposes.
Gustavo A. Seoane, PhD, is Full Professor and Head of theOrganic Chemistry Department of the Faculty of Chemistry ofUniversidad de la República, Uruguay. His main scientificinterest is the use of green procedures for the synthesis ofbioactive natural products and analogs, in particular, intensiveuse of biotransformations to prepare polyoxygenated targets. Heworks actively to promote the development of biocatalysis in SouthAmerica.
Patricia Saenz-Méndez, PhD, is Assistant Professorof Physical Organic Chemistry in the Faculty of Chemistry ofUniversidad de la República, Uruguay. She was previouslyappointed as postdoctoral fellow at the Örebro University,Sweden, and the National University of Ireland, Galway. Her work isdevoted to the experimental and in silico development ofbiotechnological and organocatalytic tools for the preparation ofhigh added-value chemicals and natural products.
Pablo Domínguez de María, PhD, is Group Leaderat the Institute for Technical and Macromolecular Chemistry (ITMC),RWTH Aachen University, Germany. He was previously affiliated withAkzoNobel BV in the Netherlands and Degussa AG in Germany. Dr.Domínguez de María has also worked as a technicalfreelance advisor on emerging technologies (e.g., catalysis)applied to sustainable chemistry (www.sustainablemomentum.net). Hewas awarded the Young Scientist Prize by the Iberoamerican Academyof Pharmacy.
