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Nuclear Medicine techniques have advanced to such a degree that biochemical transparency of the human body has reached the doorstep of medical application. The book gives background, techniques and examples in an interdisciplinary approach to quantify biochemical reactions in vivo by regional imaging and in vitro analyses. The goal is to assess in vivo biochemical homeostatic circuits under control by genes and protein interactions. It becomes apparent how nuclear medicine can aid clinical researchers and practitioners, human geneticists and pharmacologists in understanding (and affecting) gene-phenotype relationships operating in vivo and thus can help eventually to bring functional genomics and proteomics to clinical medicine.
From the reviews:
"The editors...have brilliantly analyzed [the revolution in Nuclear Medicine] by gathering an impressive set of data on genomics and proteomics... The book's emphasis on the potential applications of nuclear medicine hints at the complete transformaiton that will face this specialty in the near future...this [book] should be carefully read by all specialists and researchers in nuclear medicine and by clinicians in other fields who may find in it new fields of research or applications of their own discoveries or a way to solve clinical problems. What is more, decision makers will benefit from learning about the potential of this specialty and its future role in clinical medicine and biology." -- NEJM, April 2004
"With few exceptions, everything in nuclear medicine is molecular medicine. . In other words: what is new? The answer is this book, which focusses especially on molecular nuclear imaging and draws attention to our ability, knowledge and expertise . . This beautifully produced hard-bound volume contains carefully assembled data and in-depth discussion of the major fields of nuclear medicine. . Suffice to say that this book will remain on my desk for a long time to come." (E.K.J. Pauwels, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 31(5), 2004)
Over six hundred fifty scientific publications, especially on cell biology, molecular nuclear medicine for in vivo analysis of biochemical reactions, cell responses to low doses of ionizing radiation and to strong static magnetic fields in single- and multi- cellular systems. - Member of numerous national and international advisory groups, committees, boards. Member, Northrhine-Westfalian Academy of Sciences, Germany. Vice-president, Committee for the Annual Meetings of Nobel Prize Winners in Lindau, Germany. Numerous scientific awards and prices.
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