during the past few years increasing interest has been
focused on the role of gamma-aminobutyric acid (GABA)
outside the central nervous systems (CNS).Biochemical,
pharmacological, histochemical, physiological approaches
have all been employed to investigate the role of GABA in
themammalian periphery. The International Symposium on
Peripheral GABAergic Mechanism held in Rome, July 1990, was
devoted to gather scientists from allover the world in
order to summarize and sythesize their most recent results
and conceptions on the significance of GABA outside the
CNS. Written in a thought-provoking style, this proceedings
volume is an overviewof the timely knowledge about GABA in
the peripheral nervous system and in non-neuronal tissues.
Chapters of the book provide many examples for the diverse
functions of this amino acid in the periphery as
neurotransmitter, hormone, humoral or even trophic factor
from the autonomic ganglia to the endocrine stomach and
pancreas, from the tubular epithelium of the kidney to the
spermatozoa.
Sprache
Verlagsort
Verlagsgruppe
Illustrationen
Dateigröße
ISBN-13
978-3-642-76915-3 (9783642769153)
DOI
10.1007/978-3-642-76915-3
Schweitzer Klassifikation
GABA in the Peripheral Nervous System.- The Role of GABA in the Peripheral Nervous System.- GABAergic Neurons in the Myenteric Plexus.- GABA and Gut Motility.- The GABAergic Innervation of Paravertebral Sympathetic Ganglia.- L-Glutamate Decarboxylase Immunoreactivity in the Sympathoadrenal System.- GABAergic Action on Cholinergic Axon Terminals in the Superior Cervical Ganglion.- GABA in Non-Neural Tissues.- Non-Neuronal GABA Systems: An Overview.- GABA and Endocrine Cells of the Gastro-entero-pancreatic System: A Review.- GABA and Diamine Oxidase Activity in the Gastrointestinal Mucosa: Possible Links.- GABA and the Liver: The First 40 Years.- GABA-Immunoreactive Structures in Rat Kidney.- GABAergic Mechanisms in Bovine Adrenal Chromaffin Cells: Their Role in the Regulation of Catecholamine Secretion.- The GABAergic System in Human Female Genital Organs.- Neurotransmitter Amino Acids as Modulators of Biological Processes of Spermatozoa.- Pharmacology and GABA Receptors.- GABA Receptors Inside and Outside the Brain.- Autoradiographic Localization of Peripheral GABAA Receptors.- The GABAB Receptor Profile of a Series of Phosphinic Acids: Agonist and Antagonist Activity in a Range of Peripheral Tissues.- GABAergic Mechanisms and Cardiovascular Function.- GABAergic Mechanisms in the Pulmonary System.- GABAergic Mechanisms and Modulation of the Anaphylaxie Response.
